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Literature DB >> 22064411

An unSIRTain role in longevity.

Domenico Accili¹, Rafael de Cabo, David A Sinclair.

Abstract

Mesh：

Substances：
Sirtuin 1
Sirtuin 2

Year: 2011 PMID： 22064411 DOI： 10.1038/nm1111-1350

Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440

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12 in total

1. Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes.

Authors: Mohan Viswanathan; Leonard Guarente
Journal: Nature Date: 2011-09-21 Impact factor: 49.962

Review 2. The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity.

Authors: Akiko Satoh; Liana Stein; Shin Imai
Journal: Handb Exp Pharmacol Date: 2011

3. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.

Authors: H A Tissenbaum; L Guarente
Journal: Nature Date: 2001-03-08 Impact factor: 49.962

4. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.

Authors: Mohan Viswanathan; Stuart K Kim; Ala Berdichevsky; Leonard Guarente
Journal: Dev Cell Date: 2005-11 Impact factor: 12.270

5. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.

Authors: M Kaeberlein; M McVey; L Guarente
Journal: Genes Dev Date: 1999-10-01 Impact factor: 11.361

6. Sir2 mediates longevity in the fly through a pathway related to calorie restriction.

Authors: Blanka Rogina; Stephen L Helfand
Journal: Proc Natl Acad Sci U S A Date: 2004-11-01 Impact factor: 11.205

7. Extended longevity in mice lacking the insulin receptor in adipose tissue.

Authors: Matthias Blüher; Barbara B Kahn; C Ronald Kahn
Journal: Science Date: 2003-01-24 Impact factor: 47.728

8. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.

Authors: Gizem Rizki; Terri Naoko Iwata; Ji Li; Christian G Riedel; Colette Lafontaine Picard; Max Jan; Coleen T Murphy; Siu Sylvia Lee
Journal: PLoS Genet Date: 2011-09-01 Impact factor: 5.917

9. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.

Authors: Camilla Burnett; Sara Valentini; Filipe Cabreiro; Martin Goss; Milán Somogyvári; Matthew D Piper; Matthew Hoddinott; George L Sutphin; Vid Leko; Joshua J McElwee; Rafael P Vazquez-Manrique; Anne-Marie Orfila; Daniel Ackerman; Catherine Au; Giovanna Vinti; Michèle Riesen; Ken Howard; Christian Neri; Antonio Bedalov; Matt Kaeberlein; Csaba Soti; Linda Partridge; David Gems
Journal: Nature Date: 2011-09-21 Impact factor: 49.962

An unSIRTain role in longevity.

1. Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes.

Review 2. The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity.

3. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.

4. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.

5. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.

6. Sir2 mediates longevity in the fly through a pathway related to calorie restriction.

7. Extended longevity in mice lacking the insulin receptor in adipose tissue.

8. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.

9. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.

10. dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster.

Review 1. Protection of the heart against ischemia/reperfusion by silent information regulator 1.

2. Role of transcription factor acetylation in diabetic kidney disease.

3. SIRT1 polymorphism, long-term survival and glucose tolerance in the general population.

Review 4. Adrenergic signaling and oxidative stress: a role for sirtuins?