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Literature DB >> 2206278

Animal models for AIDS.

Abstract

Animal models will play a central role in AIDS research in the coming years. Important models for human immunodeficiency virus (HIV)-induced disease in humans include HIV-infected great apes, simian immunodeficiency virus-infected Asian monkeys and infections of ungulates and cats with HIV-related lentiviruses. The nature of the diseases induced by these viruses are described here by Norman Letvin, emphasizing aspects with particular relevance to human HIV infections.

Entities: Disease Species

Mesh：

Year: 1990 PMID： 2206278 DOI： 10.1016/0167-5699(90)90127-u

Source DB: PubMed Journal: Immunol Today ISSN： 0167-5699

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Cited

27 in total

1. In vivo T-lymphocyte activation and transient reduction of viral replication in macaques infected with simian immunodeficiency virus.

Authors: Z W Chen; Y Shen; D Zhou; M Simon; Z Kou; D Lee-Parritz; L Shen; P Sehgal; N L Letvin
Journal: J Virol Date: 2001-05 Impact factor: 5.103

Review 2. A defective HIV-1 vector for gene transfer to human lymphocytes.

Authors: C Parolin; J Sodroski
Journal: J Mol Med (Berl) Date: 1995-06 Impact factor: 4.599

Review 3. Vaccines for control of AIDS--an update.

Authors: K B Sharma
Journal: Indian J Pediatr Date: 1994 Sep-Oct Impact factor: 1.967

4. An acutely lethal simian immunodeficiency virus stimulates expansion of V beta 7- and V beta 14-expressing T lymphocytes.

Authors: Z W Chen; Z C Kou; L Shen; J D Regan; C I Lord; M Halloran; D Lee-Parritz; P N Fultz; N L Letvin
Journal: Proc Natl Acad Sci U S A Date: 1994-08-02 Impact factor: 11.205

5. Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection.

Authors: N R Klatt; L D Harris; C L Vinton; H Sung; J A Briant; B Tabb; D Morcock; J W McGinty; J D Lifson; B A Lafont; M A Martin; A D Levine; J D Estes; J M Brenchley
Journal: Mucosal Immunol Date: 2010-03-31 Impact factor: 7.313

6. Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2).

Authors: M Cayabyab; G B Karlsson; B A Etemad-Moghadam; W Hofmann; T Steenbeke; M Halloran; J W Fanton; M K Axthelm; N L Letvin; J G Sodroski
Journal: J Virol Date: 1999-02 Impact factor: 5.103

Animal models for AIDS.

1. In vivo T-lymphocyte activation and transient reduction of viral replication in macaques infected with simian immunodeficiency virus.

Review 2. A defective HIV-1 vector for gene transfer to human lymphocytes.

Review 3. Vaccines for control of AIDS--an update.

4. An acutely lethal simian immunodeficiency virus stimulates expansion of V beta 7- and V beta 14-expressing T lymphocytes.

5. Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection.

6. Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2).

7. The induction of in vivo superinfection and recombination using feline immunodeficiency virus as the model.

Review 8. Chronic alcohol abuse and HIV disease progression: studies with the non-human primate model.

9. Sequence and diversity of rhesus monkey T-cell receptor beta chain genes.

10. Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys.