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Literature DB >> 22062445

The aging brain and neurodegenerative diseases.

Abstract

This article reviews the current thoughts on the effects of aging on the brain. Mechanisms of neurodegeneration are discussed, particularly those associated with Alzheimer's and Parkinson's diseases. Strategies of early detection of presymptomatic disease and potential future treatments are explored. Modification of risk factors and lifestyles for disease prevention is discussed.

Entities: Disease

Mesh：

Year: 2011 PMID： 22062445 DOI： 10.1016/j.cger.2011.07.008

Source DB: PubMed Journal: Clin Geriatr Med ISSN： 0749-0690 Impact factor: 3.076

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Cited

11 in total

1. Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4-hydroxynonenal.

Authors: Shi Zhang; Erez Eitan; Mark P Mattson
Journal: J Neurochem Date: 2017-02-16 Impact factor: 5.372

2. Caveolin-1 Regulates the P2Y2 Receptor Signaling in Human 1321N1 Astrocytoma Cells.

Authors: Namyr A Martinez; Alondra M Ayala; Magdiel Martinez; Freddyson J Martinez-Rivera; Jorge D Miranda; Walter I Silva
Journal: J Biol Chem Date: 2016-04-18 Impact factor: 5.157

3. Up-regulation and activation of the P2Y(2) nucleotide receptor mediate neurite extension in IL-1β-treated mouse primary cortical neurons.

Authors: Troy S Peterson; Christina N Thebeau; Deepa Ajit; Jean M Camden; Lucas T Woods; W Gibson Wood; Michael J Petris; Grace Y Sun; Laurie Erb; Gary A Weisman
Journal: J Neurochem Date: 2013-04-25 Impact factor: 5.372

4. Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice.

Authors: Laura A N Peferoen; Marjolein Breur; Sarah van de Berg; Regina Peferoen-Baert; Erik H W G M Boddeke; Paul van der Valk; Gareth Pryce; Johannes M van Noort; David Baker; Sandra Amor
Journal: Immunology Date: 2016-08-09 Impact factor: 7.397

The aging brain and neurodegenerative diseases.

1. Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4-hydroxynonenal.

2. Caveolin-1 Regulates the P2Y2 Receptor Signaling in Human 1321N1 Astrocytoma Cells.

3. Up-regulation and activation of the P2Y(2) nucleotide receptor mediate neurite extension in IL-1β-treated mouse primary cortical neurons.

4. Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice.

Review 5. Neuroimaging in Parkinson disease: from research setting to clinical practice.

Review 6. Therapeutics with SPION-labeled stem cells for the main diseases related to brain aging: a systematic review.

7. Endothelial Function Is Associated with White Matter Microstructure and Executive Function in Older Adults.

Review 8. Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease.

9. Nervonic acid amends motor disorder in a mouse model of Parkinson's disease.

10. Biological sources of inflexibility in brain and behavior with aging and neurodegenerative diseases.