Literature DB >> 22062437

Theories and mechanisms of aging.

Charles A Cefalu1.   

Abstract

This article discusses various theories of aging and their relative plausibility related to the human aging process. Structural and physiologic changes of aging are discussed in detail by organ system. Each of the organ systems is discussed when applicable to the various theories of aging. Normal versus abnormal aging is discussed in the context of specific aging processes, with atypical presentations of disease and general links to life expectancy. Life expectancy and lifespan are discussed in the context of advances in medical science and the potential ultimate link to human life span.

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Mesh：

Year:  2011        PMID： 22062437     DOI： 10.1016/j.cger.2011.07.001

Source DB:  PubMed          Journal:  Clin Geriatr Med        ISSN： 0749-0690            Impact factor:   3.076


  15 in total

Review 1.  Effect of exercise training on arterial stiffness in obese and overweight children: a meta-analysis.

Authors:  Yue Cheng; Zhenjia Sun; Xudong Ya; Linlin Zhou; Mingxia Wang; Xingqi Wang; Yujia Liu
Journal:  Eur J Pediatr       Date:  2022-04-30       Impact factor: 3.183

2.  Normal ageing is associated with an increase in Th2 cells, MCP-1 (CCL1) and RANTES (CCL5), with differences in sCD40L and PDGF-AA between sexes.

Authors:  A S Mansfield; W K Nevala; R S Dronca; A A Leontovich; L Shuster; S N Markovic
Journal:  Clin Exp Immunol       Date:  2012-11       Impact factor: 4.330

Review 3.  DNA Damage, DNA Repair, Aging, and Neurodegeneration.

Authors:  Scott Maynard; Evandro Fei Fang; Morten Scheibye-Knudsen; Deborah L Croteau; Vilhelm A Bohr
Journal:  Cold Spring Harb Perspect Med       Date:  2015-09-18       Impact factor: 6.915

4.  The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases.

Authors:  Caitlin M Daimon; Patrick Chirdon; Stuart Maudsley; Bronwen Martin
Journal:  Am J Alzheimers Dis (Columbia)       Date:  2013

5.  Traumatic brain injury among older adults at level I and II trauma centers.

Authors:  Kristen Dams-O'Connor; Jeffrey P Cuthbert; John Whyte; John D Corrigan; Mark Faul; Cynthia Harrison-Felix
Journal:  J Neurotrauma       Date:  2013-11-26       Impact factor: 5.269

6.  Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction.

Authors:  Bryon R McKay; Daniel I Ogborn; Jeff M Baker; Kyle G Toth; Mark A Tarnopolsky; Gianni Parise
Journal:  Am J Physiol Cell Physiol       Date:  2013-02-07       Impact factor: 4.249

7.  Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress.

Authors:  Mohamed A Abdelmegeed; Youngshim Choi; Seung-Kwon Ha; Byoung-Joon Song
Journal:  Free Radic Biol Med       Date:  2015-12-17       Impact factor: 7.376

Review 8.  Autophagy and cardiovascular aging: lesson learned from rapamycin.

Authors:  Sreejayan Nair; Jun Ren
Journal:  Cell Cycle       Date:  2012-06-01       Impact factor: 4.534

Review 9.  Epigenetic Mechanisms Underlying the Aging of Articular Cartilage and Osteoarthritis.

Authors:  Mingcai Zhang; Justin L Theleman; Katherine A Lygrisse; Jinxi Wang
Journal:  Gerontology       Date:  2019-04-10       Impact factor: 5.597

Review 10.  Effect of antioxidants supplementation on aging and longevity.

Authors:  Izabela Sadowska-Bartosz; Grzegorz Bartosz
Journal:  Biomed Res Int       Date:  2014-03-25       Impact factor: 3.411
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