Literature DB >> 22061046

Numerical analysis of micro- and nano-particle deposition in a realistic human upper airway.

Pejman Farhadi Ghalati1, Erfan Keshavarzian, Omid Abouali, Abolhassan Faramarzi, Jiyuan Tu, Alireza Shakibafard.   

Abstract

A computational model was developed for studying the flow field and particle deposition in a human upper airway system, including: nasal cavity, nasopharynx, oropharynx, larynx and trachea. A series of coronal CT scan images of a 24 year old woman was used to construct the 3D model. The Lagrangian and Eulerian approaches were used, respectively, to find the trajectories of micro-particles and concentration of nano-particles. The total and regional deposition fractions of micro/nanoparticles were evaluated and the major hot spots for the deposition of inhaled particles were found.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 22061046     DOI: 10.1016/j.compbiomed.2011.10.005

Source DB:  PubMed          Journal:  Comput Biol Med        ISSN: 0010-4825            Impact factor:   4.589


  11 in total

1.  Ideal Particle Sizes for Inhaled Steroids Targeting Vocal Granulomas: Preliminary Study Using Computational Fluid Dynamics.

Authors:  Elizabeth L Perkins; Saikat Basu; Guilherme J M Garcia; Robert A Buckmire; Rupali N Shah; Julia S Kimbell
Journal:  Otolaryngol Head Neck Surg       Date:  2017-11-21       Impact factor: 3.497

2.  Olfactory deposition of inhaled nanoparticles in humans.

Authors:  Guilherme J M Garcia; Jeffry D Schroeter; Julia S Kimbell
Journal:  Inhal Toxicol       Date:  2015-07-21       Impact factor: 2.724

3.  Solid Anorganic Particles and Chronic Rhinosinusitis: A Histopathology Study.

Authors:  Lenka Čábalová; Kristina Čabanová; Hana Bielniková; Jana Kukutschová; Jana Dvořáčková; Karol Zeleník; Pavel Komínek
Journal:  Int J Environ Res Public Health       Date:  2022-06-14       Impact factor: 4.614

4.  Effects of chlorine particle concentration on the human airway.

Authors:  Fifi N M Elwekeel; Xinguang Cui; Antar M M Abdala
Journal:  J Nanopart Res       Date:  2022-05-20       Impact factor: 2.533

5.  Micro- and Nanosized Particles in Nasal Mucosa: A Pilot Study.

Authors:  Lenka Čábalová; Kristina Čabanová; Hana Bielniková; Jana Kukutschová; Jana Dvořáčková; Kateřina Dědková; Karol Zeleník; Pavel Komínek
Journal:  Biomed Res Int       Date:  2015-06-01       Impact factor: 3.411

6.  A combined experimental and numerical study on upper airway dosimetry of inhaled nanoparticles from an electrical discharge machine shop.

Authors:  Lin Tian; Yidan Shang; Rui Chen; Ru Bai; Chunying Chen; Kiao Inthavong; Jiyuan Tu
Journal:  Part Fibre Toxicol       Date:  2017-07-12       Impact factor: 9.400

Review 7.  A Review of Respiratory Anatomical Development, Air Flow Characterization and Particle Deposition.

Authors:  Mohammad S Islam; Gunther Paul; Hui X Ong; Paul M Young; Y T Gu; Suvash C Saha
Journal:  Int J Environ Res Public Health       Date:  2020-01-07       Impact factor: 3.390

8.  A computational study of functional endoscopic sinus surgery and maxillary sinus drug delivery.

Authors:  M R Wofford; J S Kimbell; D O Frank-Ito; V Dhandha; K A McKinney; G M Fleischman; C S Ebert; A M Zanation; B A Senior
Journal:  Rhinology       Date:  2015-03       Impact factor: 3.681

9.  Effect of pollutant source location on air pollutant dispersion around a high-rise building.

Authors:  Erfan Keshavarzian; Ruizhi Jin; Kejun Dong; Kenny C S Kwok; Yu Zhang; Ming Zhao
Journal:  Appl Math Model       Date:  2020-01-15       Impact factor: 5.129

10.  Regional deposition of the allergens and micro-aerosols in the healthy human nasal airways.

Authors:  Mohammad Hazeri; Mohammad Faramarzi; Sasan Sadrizadeh; Goodarz Ahmadi; Omid Abouali
Journal:  J Aerosol Sci       Date:  2020-10-19       Impact factor: 3.433

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