Literature DB >> 22058021

Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.

Nadia Anikeeva1, Yuri Sykulev.   

Abstract

Cytotoxic T lymphocytes (CTL) play a critical role in immunity against viruses and cancer. The antigen receptor or T-cell receptor (TCR) on CTL determines the specificity toward target cells. The CD8 co-receptor functions in concert with the TCR to enhance TCR-mediated signaling, accounting for the remarkable sensitivity and swift signaling kinetics of the CTL response. The latter ensures efficient delivery and release of lytic granules, resulting in sensitive and rapid destruction of target cells.

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Year:  2011        PMID： 22058021      PMCID： PMC3244531          DOI： 10.1007/s12026-011-8252-8

Source DB:  PubMed          Journal:  Immunol Res        ISSN： 0257-277X            Impact factor:   2.829


  102 in total

1.  Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning.

Authors:  J J Boniface; Z Reich; D S Lyons; M M Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

2.  Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity.

Authors:  Michelle Krogsgaard; Qi-Jing Li; Cenk Sumen; Johannes B Huppa; Morgan Huse; Mark M Davis
Journal:  Nature       Date:  2005-02-20       Impact factor: 49.962

3.  Tissue distribution of natural peptides derived from a ubiquitous dehydrogenase, including a novel liver-specific peptide that demonstrates the pronounced specificity of low affinity T cell reactions.

Authors:  M X Wu; T J Tsomides; H N Eisen
Journal:  J Immunol       Date:  1995-05-01       Impact factor: 5.422

4.  Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

Authors:  B K al-Ramadi; M T Jelonek; L F Boyd; D H Margulies; A L Bothwell
Journal:  J Immunol       Date:  1995-07-15       Impact factor: 5.422

5.  Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response.

Authors:  Y Sykulev; M Joo; I Vturina; T J Tsomides; H N Eisen
Journal:  Immunity       Date:  1996-06       Impact factor: 31.745

Review 6.  Positive selection of thymocytes.

Authors:  S C Jameson; K A Hogquist; M J Bevan
Journal:  Annu Rev Immunol       Date:  1995       Impact factor: 28.527

Review 7.  The three-dimensional structure of peptide-MHC complexes.

Authors:  D R Madden
Journal:  Annu Rev Immunol       Date:  1995       Impact factor: 28.527

8.  The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes.

Authors:  Y Sykulev; R J Cohen; H N Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-19       Impact factor: 11.205

9.  Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.

Authors:  Nadia Anikeeva; Kristina Somersalo; Tasha N Sims; V Kaye Thomas; Michael L Dustin; Yuri Sykulev
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-25       Impact factor: 11.205

10.  Major histocompatibility complex class I-intercellular adhesion molecule-1 association on the surface of target cells: implications for antigen presentation to cytotoxic T lymphocytes.

Authors:  Tatiana Lebedeva; Nadja Anikeeva; Spyros A Kalams; Bruce D Walker; Ibragim Gaidarov; James H Keen; Yuri Sykulev
Journal:  Immunology       Date:  2004-12       Impact factor: 7.397
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  15 in total

1.  Integrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent Manner.

Authors:  Maria Steblyanko; Nadia Anikeeva; Kerry S Campbell; James H Keen; Yuri Sykulev
Journal:  J Biol Chem       Date:  2015-03-16       Impact factor: 5.157

2.  Phenotypical and Functional Characterization of Cytotoxic Unconventional T-Cells.

Authors:  Margherita Gigante; Elena Ranieri
Journal:  Methods Mol Biol       Date:  2021

3.  Extent of MHC Clustering Regulates Selectivity and Effectiveness of T Cell Responses.

Authors:  Nadia Anikeeva; Nicholas O Fischer; Craig D Blanchette; Yuri Sykulev
Journal:  J Immunol       Date:  2018-12-12       Impact factor: 5.422

4.  Cytotoxic immunological synapses do not restrict the action of interferon-γ to antigenic target cells.

Authors:  Nicholas Stephen Rennie Sanderson; Mariana Puntel; Kurt M Kroeger; Niyati S Bondale; Mark Swerdlow; Niloufar Iranmanesh; Hideo Yagita; Ahmed Ibrahim; Maria G Castro; Pedro R Lowenstein
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-30       Impact factor: 11.205

5.  Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner.

Authors:  Talyn Chu; Aaron J Tyznik; Sarah Roepke; Amy M Berkley; Amanda Woodward-Davis; Laura Pattacini; Michael J Bevan; Dietmar Zehn; Martin Prlic
Journal:  Cell Rep       Date:  2013-03-21       Impact factor: 9.423

6.  CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.

Authors:  Marina Durward-Diioia; Jerome Harms; Mike Khan; Cherisse Hall; Judith A Smith; Gary A Splitter
Journal:  Infect Immun       Date:  2015-09-28       Impact factor: 3.441

7.  Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue.

Authors:  Maria Steblyanko; Nadia Anikeeva; Marcus Buggert; Michael R Betts; Yuri Sykulev
Journal:  J Vis Exp       Date:  2018-07-30       Impact factor: 1.355

8.  Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling.

Authors:  Nadia Anikeeva; Dimitry Gakamsky; Jørgen Schøller; Yuri Sykulev
Journal:  PLoS One       Date:  2012-08-03       Impact factor: 3.240

9.  Effect of type of TAG fatty acids on lutein and zeaxanthin bioavailability.

Authors:  Béatrice Gleize; Franck Tourniaire; Laurence Depezay; Romain Bott; Marion Nowicki; Lionel Albino; Denis Lairon; Emmanuelle Kesse-Guyot; Pilar Galan; Serge Hercberg; Patrick Borel
Journal:  Br J Nutr       Date:  2012-12-11       Impact factor: 3.718

10.  An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport.

Authors:  Marlieke L M Jongsma; Ilana Berlin; Ruud H M Wijdeven; Lennert Janssen; George M C Janssen; Malgorzata A Garstka; Hans Janssen; Mark Mensink; Peter A van Veelen; Robbert M Spaapen; Jacques Neefjes
Journal:  Cell       Date:  2016-06-30       Impact factor: 41.582
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