BACKGROUND: Mycobacterium malmoense is a nontuberculous mycobacteria seen mainly in two age groups and with different clinical presentations. Most patients are male adults presenting clinical symptoms and signs similar to those of pulmonary tuberculosis. The second group is formed by immunocompetent children with localized cervical lymphadenitis. Although cervical adenitis is the main extrapulmonary manifestation of M. malmoense, virtually all cases of cervical disease were documented in children. Disseminated disease is rare and has been reported in patients with severely impaired immunity. CASE REPORT: We report a case of a 47-year-old immunocompetent man with a cervical abscess, in whom we identified a M. malmoense pulmonary disease with multiple cervical, thoracic and abdominal adenopathies. CONCLUSION: Extrapulmonary infection due to M. Malmoense needs to be considered on the differential diagnosis of cervical masses and adenopathies, not only in pediatric patients but also in adults with no impaired immunity. A high index of suspicion for nontuberculous mycobacteria is essential for the diagnosis and prognosis.
BACKGROUND:Mycobacterium malmoense is a nontuberculous mycobacteria seen mainly in two age groups and with different clinical presentations. Most patients are male adults presenting clinical symptoms and signs similar to those of pulmonary tuberculosis. The second group is formed by immunocompetent children with localized cervical lymphadenitis. Although cervical adenitis is the main extrapulmonary manifestation of M. malmoense, virtually all cases of cervical disease were documented in children. Disseminated disease is rare and has been reported in patients with severely impaired immunity. CASE REPORT: We report a case of a 47-year-old immunocompetent man with a cervical abscess, in whom we identified a M. malmoensepulmonary disease with multiple cervical, thoracic and abdominal adenopathies. CONCLUSION:Extrapulmonary infection due to M. Malmoense needs to be considered on the differential diagnosis of cervical masses and adenopathies, not only in pediatric patients but also in adults with no impaired immunity. A high index of suspicion for nontuberculous mycobacteria is essential for the diagnosis and prognosis.
Authors: N Martín-Casabona; A R Bahrmand; J Bennedsen; V Ostergaard Thomsen; M Curcio; M Fauville-Dufaux; K Feldman; M Havelkova; M L Katila; K Köksalan; M F Pereira; F Rodrigues; G E Pfyffer; F Portaels; J Rosselló Urgell; S Rüsch-Gerdes; E Tortoli; V Vincent; B Watt Journal: Int J Tuberc Lung Dis Date: 2004-10 Impact factor: 2.373
Authors: Jakko van Ingen; Tridia van der Laan; Richard Dekhuijzen; Martin Boeree; Dick van Soolingen Journal: Int J Antimicrob Agents Date: 2009-12-16 Impact factor: 5.283
Authors: Jerome A Lindeboom; Ed J Kuijper; Elisabeth S Bruijnesteijn van Coppenraet; Robert Lindeboom; Jan M Prins Journal: Clin Infect Dis Date: 2007-03-02 Impact factor: 9.079