BACKGROUND: The association between soft drink (SD) consumption and Helicobacter pylori infection remains unclear. AIM: To examine the relationship between SD consumption and H. pylori infection. METHODS: A prospective study included individuals who were referred for an upper gastrointestinal endoscopic examination because chronic dyspepsia within a period of 1 year. In addition to determining daily SD consumption and the risk factors for H. pylori infection by asking all study participants to complete a standard questionnaire about their diet, daily eating and drinking habits, and their lifestyle before undergoing the endoscopic examination. H. pylori infection was established by a positive result of the rapid urease test and histology. RESULTS: Of the 312 individuals who were referred for the endoscopic examination because chronic dyspepsia, 269 met the inclusion criteria. H. pylori infection was found in 164 (61%) of the 269 study participants, and, of these, 104/164 individuals were SD consumers with H. pylori infection versus 24/105 individuals without H. pylori infection (63 vs. 23%, respectively, P < 0.001). The results of the multiple logistic regression analysis showed that SD consumption (odds ratio = 4.0; 95 % confidence interval = 3.19–5.82,P < 0.001), was associated with H. pylori infection. CONCLUSION: SD consumption is associated with H. pylori infection in individuals with chronic dyspepsia.
BACKGROUND: The association between soft drink (SD) consumption and Helicobacter pylori infection remains unclear. AIM: To examine the relationship between SD consumption and H. pyloriinfection. METHODS: A prospective study included individuals who were referred for an upper gastrointestinal endoscopic examination because chronic dyspepsia within a period of 1 year. In addition to determining daily SD consumption and the risk factors for H. pyloriinfection by asking all study participants to complete a standard questionnaire about their diet, daily eating and drinking habits, and their lifestyle before undergoing the endoscopic examination. H. pyloriinfection was established by a positive result of the rapid urease test and histology. RESULTS: Of the 312 individuals who were referred for the endoscopic examination because chronic dyspepsia, 269 met the inclusion criteria. H. pyloriinfection was found in 164 (61%) of the 269 study participants, and, of these, 104/164 individuals were SD consumers with H. pyloriinfection versus 24/105 individuals without H. pyloriinfection (63 vs. 23%, respectively, P < 0.001). The results of the multiple logistic regression analysis showed that SD consumption (odds ratio = 4.0; 95 % confidence interval = 3.19–5.82,P < 0.001), was associated with H. pyloriinfection. CONCLUSION: SD consumption is associated with H. pyloriinfection in individuals with chronic dyspepsia.
Authors: S J Veldhuyzen van Zanten; N Flook; N Chiba; D Armstrong; A Barkun; M Bradette; A Thomson; F Bursey; P Blackshaw; D Frail; P Sinclair Journal: CMAJ Date: 2000-06-13 Impact factor: 8.262
Authors: A Ogihara; S Kikuchi; A Hasegawa; M Kurosawa; K Miki; E Kaneko; H Mizukoshi Journal: J Gastroenterol Hepatol Date: 2000-03 Impact factor: 4.029
Authors: Paul Moayyedi; Anthony T R Axon; Richard Feltbower; Sara Duffett; Will Crocombe; David Braunholtz; I D Gerald Richards; Anthony C Dowell; David Forman Journal: Int J Epidemiol Date: 2002-06 Impact factor: 7.196