Literature DB >> 22056827

Severity of obstructive sleep apnea between black and white patients.

Ammar Alkhazna1, Abid Bhat, James Ladesich, Brandon Barthel, Aaron J Bohnam.   

Abstract

Obstructive sleep apnea (OSA) is a relatively common problem with potentially serious health consequences. The purpose of this study was to identify whether race has any effect on the severity of OSA. Our hypothesis was that OSA, when present, is more severe in black patients than white patients. This cross-sectional study was performed at Truman Medical Centers, a teaching hospital affiliated with University of Missouri-Kansas City School of Medicine (Kansas City, MO). Multiple linear regression analysis was conducted to establish if race was predictive of apnea-hypopnea index (AHI) score when controlling for age, sex, and body mass index. The analysis included 280 patients with complete data for each of the variables in the model. Race (the primary predictor of interest) did not significantly predict AHI score (P = 0.172), and neither did age (P = 0.783). Men had higher AHI scores than women (P < 0.001), and higher body mass index was associated with higher AHI score (P < 0.001). There were more black women in the sample population than white women (P = 0.043). Black patients were also more likely to have hypertension (P = 0.037). This study suggests that race is not a predictor of OSA severity after controlling for age, sex, and body mass index. There is a need for more studies to examine the prevalence of OSA in different races.

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Year:  2011        PMID: 22056827     DOI: 10.3810/hp.2011.10.926

Source DB:  PubMed          Journal:  Hosp Pract (1995)        ISSN: 2154-8331


  4 in total

Review 1.  Disparities and genetic risk factors in obstructive sleep apnea.

Authors:  Katherine A Dudley; Sanjay R Patel
Journal:  Sleep Med       Date:  2015-02-27       Impact factor: 3.492

2.  Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men.

Authors:  Han Chen; Brian E Cade; Kevin J Gleason; Andrew C Bjonnes; Adrienne M Stilp; Tamar Sofer; Matthew P Conomos; Sonia Ancoli-Israel; Raanan Arens; Ali Azarbarzin; Graeme I Bell; Jennifer E Below; Sung Chun; Daniel S Evans; Ralf Ewert; Alexis C Frazier-Wood; Sina A Gharib; José Haba-Rubio; Erika W Hagen; Raphael Heinzer; David R Hillman; W Craig Johnson; Zoltan Kutalik; Jacqueline M Lane; Emma K Larkin; Seung Ku Lee; Jingjing Liang; Jose S Loredo; Sutapa Mukherjee; Lyle J Palmer; George J Papanicolaou; Thomas Penzel; Paul E Peppard; Wendy S Post; Alberto R Ramos; Ken Rice; Jerome I Rotter; Scott A Sands; Neomi A Shah; Chol Shin; Katie L Stone; Beate Stubbe; Jae Hoon Sul; Mehdi Tafti; Kent D Taylor; Alexander Teumer; Timothy A Thornton; Gregory J Tranah; Chaolong Wang; Heming Wang; Simon C Warby; D Andrew Wellman; Phyllis C Zee; Craig L Hanis; Cathy C Laurie; Daniel J Gottlieb; Sanjay R Patel; Xiaofeng Zhu; Shamil R Sunyaev; Richa Saxena; Xihong Lin; Susan Redline
Journal:  Am J Respir Cell Mol Biol       Date:  2018-03       Impact factor: 6.914

Review 3.  Genetic Ancestry for Sleep Research: Leveraging Health Inequalities to Identify Causal Genetic Variants.

Authors:  Bharati Prasad; Richa Saxena; Namni Goel; Sanjay R Patel
Journal:  Chest       Date:  2018-03-28       Impact factor: 9.410

4.  Racial Differences in Functional and Sleep Outcomes with Positive Airway Pressure Treatment.

Authors:  Ikuyo Imayama; Bilgay Izci Balserak; Ahana Gupta; Tomas Munoz; Manassawee Srimoragot; Brendan T Keenan; Samuel T Kuna; Bharati Prasad
Journal:  Diagnostics (Basel)       Date:  2021-11-23
  4 in total

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