Literature DB >> 220551

Different effects of K+ and Ca++ on alpha-MSH and ACTH release from superfused neurointermediate lobe of the rat hypophysis.

G Schmitt, B Briaud, C Mialhe, F Stutinsky.   

Abstract

The effects of K+-enhanced and Ca++-free media on alpha-MSH and adrenocorticotropic hormone (ACTH) release from superfused neurointermediate lobe (NIL) were studied in the same experiments. High K+ caused reversible and repeatable inhibition of alpha-MSH release and stimulation of ACTH release, Removal of Ca++ impaired the effect of K+, irreversibly for alpha-MSH and reversibly for ACTH. The existence of both melanotrophic and corticotrophic cells within the intermediate lobe (IL) of rat hypophysis could account for the different effects of ionic modifications on in vitro alpha-MSH and ACTH release.

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Year:  1979        PMID： 220551     DOI： 10.1159/000122875

Source DB:  PubMed          Journal:  Neuroendocrinology        ISSN： 0028-3835            Impact factor:   4.914


  7 in total

1.  Immunocytochemical evidence of intragranular acetylation of alpha-MSH in the melanotrophic cells of the rabbit.

Authors:  M E Stoeckel; S Schimchowitsch; J C Garaud; G Schmitt; H Vaudry; A Porte
Journal:  Cell Tissue Res       Date:  1983       Impact factor: 5.249

2.  Stimulation of calcium-dependent release of labelled protein from pulse-labelled mouse pituitary intermediate lobe tissue.

Authors:  V F Thornton
Journal:  J Physiol       Date:  1982-08       Impact factor: 5.182

3.  Plasma concentration and vascular effect of beta-endorphin in spontaneously hypertensive and Wistar Kyoto rats.

Authors:  B Bucher; R Bettermann; P Illes
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-04       Impact factor: 3.000

4.  Immunocytochemical evidence for intragranular processing of pro-opiomelanocortin in the melanotropic cells of the rabbit.

Authors:  M E Stoeckel; S Schimchowitsch; J C Garaud; G Schmitt; H Vaudry; M J Klein; A Porte
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

5.  Dual population of GABAA and GABAB receptors in rat pars intermedia demonstrated by release of alpha MSH caused by barium ions.

Authors:  B A Demeneix; E Desaulles; P Feltz; J P Loeffler
Journal:  Br J Pharmacol       Date:  1984-05       Impact factor: 8.739

6.  The effect of reserpine on the pars intermedia of the rat pituitary. An electron-microscopic, fluorescence-histochemical and immunohistochemical study.

Authors:  N Bäck; L Rechardt
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

7.  Differentiation of the melanotrophic cells of rat pituitary primordium in organotypic culture in defined medium.

Authors:  P Vuillez; F René; M Plante; C Hindelang; M J Klein; J M Félix; M E Stoeckel
Journal:  Cell Tissue Res       Date:  1992-01       Impact factor: 5.249
  7 in total

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