Literature DB >> 22053091

Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study).

Mona Razavian1, Emma L Heeley, Vlado Perkovic, Sophia Zoungas, Andrew Weekes, Anushka A Patel, Craig S Anderson, John P Chalmers, Alan Cass.   

Abstract

BACKGROUND: Chronic kidney disease (CKD) is common and increasing in prevalence. Adverse outcomes of CKD can be prevented through early detection and treatment. There is limited data on the awareness of CKD and the quality of care offered to patients with CKD in the primary care setting. The objectives of this study were to assess the prevalence, general practitioner (GP) awareness and extent of current evidence-practice gaps in the management of CKD in Australian primary care.
METHODS: The Australian Hypertension and Absolute Risk Study (AusHEART) was a nationally representative, cluster stratified, cross-sectional survey among 322 GPs. Each GP was asked to provide data for 15-20 consecutive patients (age ≥ 55 years) who presented between April and June, 2008. The main outcome measures were CKD prevalence based on proteinuria and decreased estimated glomerular filtration rate. Evidence-practice gaps in management of patients with CKD were identified.
RESULTS: Among a total of 4966 patients with kidney function test data, 1845 (37%) had abnormal kidney function. Of the 1312 patients with abnormal kidney function known to the GP at the time of visit, only 235 were correctly identified as having CKD. GPs under-estimated cardiovascular (CV) risks in patients with CKD when compared with the prevailing guidelines at the time of survey and the recent national guidelines, particularly in later stages of CKD. Among CKD patients not prescribed blood pressure-lowering agents or lipid-lowering agents, treatment was indicated as per relevant guidelines in 51 and 46%, respectively. For CKD patients who were already prescribed blood pressure-lowering and lipid-lowering agents, 61 and 50%, respectively, did not meet the treatment targets recommended by the relevant guidelines.
CONCLUSIONS: CKD is common, significantly under-recognized and under-treated in primary care. Effort to increase awareness and provide opportunities for improved screening and assessment should improve the management and outcome of these patients at high risk of CV disease.

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Year:  2011        PMID: 22053091     DOI: 10.1093/ndt/gfr599

Source DB:  PubMed          Journal:  Nephrol Dial Transplant        ISSN: 0931-0509            Impact factor:   5.992


  18 in total

1.  Quality indicators for the detection and management of chronic kidney disease in primary care in Canada derived from a modified Delphi panel approach.

Authors:  Karen Tu; Lindsay Bevan; Katie Hunter; Jess Rogers; Jacqueline Young; Gihad Nesrallah
Journal:  CMAJ Open       Date:  2017-01-25

Review 2.  Early chronic kidney disease: diagnosis, management and models of care.

Authors:  Olivier J Wouters; Donal J O'Donoghue; James Ritchie; Panos G Kanavos; Andrew S Narva
Journal:  Nat Rev Nephrol       Date:  2015-06-09       Impact factor: 28.314

3.  Using Classification and Regression Trees (CART) to Identify Prescribing Thresholds for Cardiovascular Disease.

Authors:  Chris Schilling; Duncan Mortimer; Kim Dalziel; Emma Heeley; John Chalmers; Philip Clarke
Journal:  Pharmacoeconomics       Date:  2016-02       Impact factor: 4.981

4.  Documentation and management of CKD in rural primary care.

Authors:  Maya K Rao; Cynthia D Morris; Jean P O'Malley; Melinda M Davis; Motomi Mori; Sharon Anderson
Journal:  Clin J Am Soc Nephrol       Date:  2013-01-31       Impact factor: 8.237

5.  Implementation of the KDIGO guideline on lipid management requires a substantial increase in statin prescription rates.

Authors:  Markus P Schneider; Silvia Hübner; Stephanie I Titze; Matthias Schmid; Jennifer Nadal; Georg Schlieper; Martin Busch; Seema Baid-Agrawal; Vera Krane; Christoph Wanner; Florian Kronenberg; Kai-Uwe Eckardt
Journal:  Kidney Int       Date:  2015-09-02       Impact factor: 10.612

Review 6.  Dedicated kidney disease-focused outcome trials with sodium-glucose cotransporter-2 inhibitors: Lessons from CREDENCE and expectations from DAPA-HF, DAPA-CKD, and EMPA-KIDNEY.

Authors:  Jinnie J Rhee; Meg J Jardine; Glenn M Chertow; Kenneth W Mahaffey
Journal:  Diabetes Obes Metab       Date:  2020-04       Impact factor: 6.577

7.  Perceptions of prognostic risks in chronic kidney disease: a national survey.

Authors:  Helen H L Chiu; Navdeep Tangri; Ognjenka Djurdjev; Brendan J Barrett; Brenda R Hemmelgarn; François Madore; Claudio Rigatto; Norman Muirhead; Manish M Sood; Catherine M Clase; Adeera Levin
Journal:  Can J Kidney Health Dis       Date:  2015-12-20

8.  Provision of care for chronic kidney disease by non-nephrologists in a developing nation: a national survey.

Authors:  S Al Shamsi; A Al Dhanhani; M M Sheek-Hussein; O Bakoush
Journal:  BMJ Open       Date:  2016-08-01       Impact factor: 2.692

9.  The Preventable Productivity Burden of Kidney Disease in Australia.

Authors:  Feby Savira; Zanfina Ademi; Bing H Wang; Andrew R Kompa; Alice J Owen; Danny Liew; Ella Zomer
Journal:  J Am Soc Nephrol       Date:  2021-03-09       Impact factor: 10.121

Review 10.  CKD Screening and Surveillance in Australia: Past, Present, and Future.

Authors:  Sree K Venuthurupalli; Wendy E Hoy; Helen G Healy; Anne Cameron; Robert G Fassett
Journal:  Kidney Int Rep       Date:  2017-10-06
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