BACKGROUND: As the number of soft tissue filler injections increases, the number of adverse events associated with injection may rise. Impending necrosis represents a serious complication that, if not treated correctly and timely, may have grave consequences. OBJECTIVE: We describe a protocol utilizing hyaluronidase, nitroglycerin paste, aspirin, antacid and a topical oxygen therapy that may be used to treat impending necrosis subsequent to injection with soft tissue fillers. CONCLUSION: We have successfully treated nine post-filler injection adverse events involving impending necrosis or necrosis following both hyaluronic acid and calcium hydroxylapatite injections using our protocol.
BACKGROUND: As the number of soft tissue filler injections increases, the number of adverse events associated with injection may rise. Impending necrosis represents a serious complication that, if not treated correctly and timely, may have grave consequences. OBJECTIVE: We describe a protocol utilizing hyaluronidase, nitroglycerin paste, aspirin, antacid and a topical oxygen therapy that may be used to treat impending necrosis subsequent to injection with soft tissue fillers. CONCLUSION: We have successfully treated nine post-filler injection adverse events involving impending necrosis or necrosis following both hyaluronic acid and calcium hydroxylapatite injections using our protocol.
Authors: Jani van Loghem; David Funt; Tatjana Pavicic; Kate Goldie; Yana Yutskovskaya; Sabrina Fabi; Pieter Siebenga; Job Thuis; Joseph Hkeik; Jonathan Kadouch; Welf Prager; Nabila Azib; Gabriela Casabona; Steve Dayan; Shino Bay Aguilera; Philippe Snozzi; Peerooz Saeed Journal: J Cosmet Dermatol Date: 2020-03-17 Impact factor: 2.696