Literature DB >> 22050889

Tumor bombesin analog loaded long-circulating and pH-sensitive liposomes as tool for tumor identification.

André Luís Branco de Barros1, Luciene das Graças Mota, Daniel Crístian Ferreira Soares, Marina Melo Antunes Coelho, Mônica Cristina Oliveira, Valbert Nascimento Cardoso.   

Abstract

Long-circulating and pH-sensitive liposomes trapping (99m)Tc-HYNIC-βAla-bombesin((7-14)) (aSpHL-(99m)Tc-BBN((7-14))) were successfully prepared. Biodistribution studies and scintigraphic images were performed in Ehrlich tumor-bearing Swiss mice. This system showed high accumulation in tumor tissue with high tumor-to-muscle ratio. Therefore, aSpHL-(99m)Tc-BBN((7-14)) could be considered as a potential agent for tumor diagnosis. Published by Elsevier Ltd.

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Year:  2011        PMID： 22050889     DOI： 10.1016/j.bmcl.2011.10.016

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

Review 1.  Radiolabeled bombesin derivatives for preclinical oncological imaging.

Authors:  Carolina de Aguiar Ferreira; Leonardo Lima Fuscaldi; Danyelle M Townsend; Domenico Rubello; André Luís Branco de Barros
Journal:  Biomed Pharmacother       Date:  2016-12-29       Impact factor: 6.529

Review 2.  Bombesin related peptides/receptors and their promising therapeutic roles in cancer imaging, targeting and treatment.

Authors:  Paola Moreno; Irene Ramos-Álvarez; Terry W Moody; Robert T Jensen
Journal:  Expert Opin Ther Targets       Date:  2016-03-28       Impact factor: 6.902

3.  pH-Sensitive, Long-Circulating Liposomes as an Alternative Tool to Deliver Doxorubicin into Tumors: a Feasibility Animal Study.

Authors:  Juliana O Silva; Renata S Fernandes; Sávia C A Lopes; Valbert N Cardoso; Elaine A Leite; Geovanni D Cassali; Maria Cristina Marzola; Domenico Rubello; Monica C Oliveira; Andre Luis Branco de Barros
Journal:  Mol Imaging Biol       Date:  2016-12       Impact factor: 3.488

4.  Influence of PEG coating on the biodistribution and tumor accumulation of pH-sensitive liposomes.

Authors:  Shirleide Santos Nunes; Renata Salgado Fernandes; Carolina Henriques Cavalcante; Isabela da Costa César; Elaine Amaral Leite; Sávia Caldeira Araújo Lopes; Alice Ferretti; Domenico Rubello; Danyelle M Townsend; Mônica Cristina de Oliveira; Valbert Nascimento Cardoso; André Luís Branco de Barros
Journal:  Drug Deliv Transl Res       Date:  2019-02       Impact factor: 4.617

5.  Emerging role of radiolabeled nanoparticles as an effective diagnostic technique.

Authors:  Andréluís Branco de Barros; Andrew Tsourkas; Babak Saboury; Valbert Nascimento Cardoso; Abass Alavi
Journal:  EJNMMI Res       Date:  2012-07-18       Impact factor: 3.138

6.  pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment.

Authors:  Shirleide Santos Nunes; Sued Eustaquio Mendes Miranda; Juliana de Oliveira Silva; Renata Salgado Fernandes; Janaína de Alcântara Lemos; Carolina de Aguiar Ferreira; Danyelle M Townsend; Geovanni Dantas Cassali; Mônica Cristina Oliveira; André Luís Branco de Barros
Journal:  Biomed Pharmacother       Date:  2021-10-08       Impact factor: 7.419

7.  PEGylated versus Non-PEGylated pH-Sensitive Liposomes: New Insights from a Comparative Antitumor Activity Study.

Authors:  Shirleide Santos Nunes; Juliana de Oliveira Silva; Renata Salgado Fernandes; Sued Eustaquio Mendes Miranda; Elaine Amaral Leite; Marcelo Alexandre de Farias; Rodrigo Villares Portugal; Geovanni Dantas Cassali; Danyelle M Townsend; Mônica Cristina Oliveira; André Luís Branco de Barros
Journal:  Pharmaceutics       Date:  2022-01-24       Impact factor: 6.321

8.  The involvement of extracellular vesicles in the transcytosis of nanoliposomes through brain endothelial cells, and the impact of liposomal pH-sensitivity.

Authors:  Joy N Reginald-Opara; Darren Svirskis; Song Yee Paek; Mingtan Tang; Simon J O'Carroll; Justin M Dean; Lawrence W Chamley; Zimei Wu
Journal:  Mater Today Bio       Date:  2022-02-05

9.  Evaluation of (99m)Tc-HYNIC-βAla-Bombesin(7-14) as an agent for pancreas tumor detection in mice.

Authors:  F N Carlesso; L L Fuscaldi; R S Araújo; C S Teixeira; M C Oliveira; S O A Fernandes; G D Cassali; D C Reis; A L B Barros; V N Cardoso
Journal:  Braz J Med Biol Res       Date:  2015-05-19       Impact factor: 2.590
  9 in total

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