OBJECTIVE: To provide normative data for canine whole retinal thickness (WRT), nerve fiber layer thickness (NFL), photoreceptor layer thickness (PR), and outer nuclear layer thickness (ONL) using spectral domain optical coherence tomography. ANIMAL STUDIED: Twelve healthy adult intact female beagles. PROCEDURE: Horizontal volume scans through the area dorso-temporal from the optic nerve (superior retina), and the area ventro-temporal from the optic nerve (inferior retina) were used to evaluate the thickness of retinal NFL, PR, ONL, and WRT. Peripapillary circular scans were used to evaluate NFL thickness. Statistical analyses were performed to compare the thickness of the individual layers between the superior and inferior retina (paired t-test). One-way analysis of variance (ANOVA) was used to compare the thickness of peripapillary NFL between the superior, inferior, temporal and nasal quadrants of the circle scan. RESULTS: The WRT, PR, and NFL thickness were greater in the superior than in the inferior retina (198.7 ± 9.6 μm vs. 164.4 ± 6.4 μm, P < 0.0001; 95.5 ± 6.5 μm vs. 78.8 ± 7.4 μm, P < 0.0001; and 26.4 ± 1.6 μm vs. 25.0 ± 1.9 μm, P = 0.0236, respectively). No statistical difference was found between the ONL thickness of the superior and inferior retina (50.1 ± 6.4 μm vs. 44.3 ± 3.6, P = 0.0578). Peripapillary NFL thickness showed a similar tendency as the linear scans, with the superior quadrant having the greatest thickness (91.26 ± 7.0 μm) and the inferior quadrant being the thinnest (76.42 ± 9.2 μm) (P < 0.001). CONCLUSIONS: Results of our in vivo studies showed significant differences between thickness values for the superior (tapetal) and inferior (nontapetal) retinal regions.
OBJECTIVE: To provide normative data for canine whole retinal thickness (WRT), nerve fiber layer thickness (NFL), photoreceptor layer thickness (PR), and outer nuclear layer thickness (ONL) using spectral domain optical coherence tomography. ANIMAL STUDIED: Twelve healthy adult intact female beagles. PROCEDURE: Horizontal volume scans through the area dorso-temporal from the optic nerve (superior retina), and the area ventro-temporal from the optic nerve (inferior retina) were used to evaluate the thickness of retinal NFL, PR, ONL, and WRT. Peripapillary circular scans were used to evaluate NFL thickness. Statistical analyses were performed to compare the thickness of the individual layers between the superior and inferior retina (paired t-test). One-way analysis of variance (ANOVA) was used to compare the thickness of peripapillary NFL between the superior, inferior, temporal and nasal quadrants of the circle scan. RESULTS: The WRT, PR, and NFL thickness were greater in the superior than in the inferior retina (198.7 ± 9.6 μm vs. 164.4 ± 6.4 μm, P < 0.0001; 95.5 ± 6.5 μm vs. 78.8 ± 7.4 μm, P < 0.0001; and 26.4 ± 1.6 μm vs. 25.0 ± 1.9 μm, P = 0.0236, respectively). No statistical difference was found between the ONL thickness of the superior and inferior retina (50.1 ± 6.4 μm vs. 44.3 ± 3.6, P = 0.0578). Peripapillary NFL thickness showed a similar tendency as the linear scans, with the superior quadrant having the greatest thickness (91.26 ± 7.0 μm) and the inferior quadrant being the thinnest (76.42 ± 9.2 μm) (P < 0.001). CONCLUSIONS: Results of our in vivo studies showed significant differences between thickness values for the superior (tapetal) and inferior (nontapetal) retinal regions.
Authors: Bhavna J Antony; Michael D Abràmoff; Matthew M Harper; Woojin Jeong; Elliott H Sohn; Young H Kwon; Randy Kardon; Mona K Garvin Journal: Biomed Opt Express Date: 2013-11-01 Impact factor: 3.732
Authors: Valérie L Dufour; Yinxi Yu; Wei Pan; Gui-Shuang Ying; Gustavo D Aguirre; William A Beltran Journal: Exp Eye Res Date: 2020-01-10 Impact factor: 3.467
Authors: Elisa Mischi; Petr Soukup; Christine D Harman; Kazuya Oikawa; Malwina E Kowalska; Sonja Hartnack; Gillian J McLellan; András M Komáromy; Simon A Pot Journal: Vet Ophthalmol Date: 2022-05-25 Impact factor: 1.444
Authors: Bhavna J Antony; Woojin Jeong; Michael D Abràmoff; Joseph Vance; Elliott H Sohn; Mona K Garvin Journal: Transl Vis Sci Technol Date: 2014-10-03 Impact factor: 3.283
Authors: F M Mowat; K R Gornik; A Dinculescu; S L Boye; W W Hauswirth; S M Petersen-Jones; J T Bartoe Journal: Gene Ther Date: 2013-11-14 Impact factor: 5.250