Literature DB >> 2205057

Modulation of host defense by the neuropeptide alpha-MSH.

J M Lipton1.   

Abstract

alpha-melanocyte stimulating hormone (alpha-MSH), a peptide that occurs within the brain, the circulation, and other body sites, is a potent antipyretic agent when given centrally or peripherally. The peptide likewise inhibits inflammation and aspects of the acute-phase response. The combined evidence suggests that alpha-MSH molecules act as natural modulators of host reactions by antagonizing the central and peripheral actions of cytokines.

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Year:  1990        PMID: 2205057      PMCID: PMC2589306     

Source DB:  PubMed          Journal:  Yale J Biol Med        ISSN: 0044-0086


  45 in total

1.  Effect of alpha- and betamelanocyte stimulating hormones on the skin colour of man.

Authors:  A B LERNER; J S MCGUIRE
Journal:  Nature       Date:  1961-01-21       Impact factor: 49.962

2.  Visualization and characterization of interleukin 1 receptors in brain.

Authors:  W L Farrar; P L Kilian; M R Ruff; J M Hill; C B Pert
Journal:  J Immunol       Date:  1987-07-15       Impact factor: 5.422

3.  The presence of two alpha-MSH positive cell groups in rat hypothalamus.

Authors:  S J Watson; H Akil
Journal:  Eur J Pharmacol       Date:  1979-09-01       Impact factor: 4.432

Review 4.  The opiomelanotropinergic neuronal and endocrine systems.

Authors:  T L O'Donohue; D M Dorsa
Journal:  Peptides       Date:  1982 May-Jun       Impact factor: 3.750

5.  Effects of peptide hormones in urate crystal inflammation.

Authors:  C W Denko; P Gabriel
Journal:  J Rheumatol       Date:  1985-10       Impact factor: 4.666

6.  Peripheral administration of alpha-MSH reduces fever in older and younger rabbits.

Authors:  M T Murphy; J M Lipton
Journal:  Peptides       Date:  1982 Sep-Oct       Impact factor: 3.750

7.  Human lymphocyte production of corticotropin and endorphin-like substances: association with leukocyte interferon.

Authors:  E M Smith; J E Blalock
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

8.  Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1.

Authors:  J G Cannon; J B Tatro; S Reichlin; C A Dinarello
Journal:  J Immunol       Date:  1986-10-01       Impact factor: 5.422

9.  Neuropeptide regulation of inflammatory and immunologic responses. The capacity of alpha-melanocyte-stimulating hormone to inhibit tumor necrosis factor and IL-1-inducible biologic responses.

Authors:  B Robertson; K Dostal; R A Daynes
Journal:  J Immunol       Date:  1988-06-15       Impact factor: 5.422

10.  Structure-activity studies with ACTH/alpha-MSH fragments on corticosteroid secretion of isolated zona glomerulosa and fasciculata cells.

Authors:  K S Szalay; D De Wied; E Stark; G Folly
Journal:  Regul Pept       Date:  1985-07
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  7 in total

1.  Perioperative measurements of IL-6 and α-melanocyte stimulating hormone in a cardiac transplant patient after ventricular assist device support.

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Journal:  J Anesth       Date:  1995-03       Impact factor: 2.078

Review 2.  Role of proopiomelanocortin-derived peptides and their receptors in the osteoarticular system: from basic to translational research.

Authors:  Markus Böhm; Susanne Grässel
Journal:  Endocr Rev       Date:  2012-06-26       Impact factor: 19.871

3.  Inhibition of acute inflammation in the periphery by central action of salicylates.

Authors:  A Catania; J Arnold; A Macaluso; M E Hiltz; J M Lipton
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-01       Impact factor: 11.205

4.  Immunosuppressive effects of corticotropin and melanotropin and their possible significance in human immunodeficiency virus infection.

Authors:  E M Smith; T K Hughes; F Hashemi; G B Stefano
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-15       Impact factor: 11.205

Review 5.  Uveitis and gender: the course of uveitis in pregnancy.

Authors:  Nathalie P Y Chiam; Lyndell L P Lim
Journal:  J Ophthalmol       Date:  2014-01-09       Impact factor: 1.909

Review 6.  Melanocortin Regulation of Inflammation.

Authors:  Wei Wang; Dong-Yu Guo; Yue-Jun Lin; Ya-Xiong Tao
Journal:  Front Endocrinol (Lausanne)       Date:  2019-10-09       Impact factor: 5.555

Review 7.  Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis?

Authors:  Susanne Grässel; Dominique Muschter
Journal:  Int J Mol Sci       Date:  2018-01-26       Impact factor: 5.923

  7 in total

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