| Literature DB >> 22045163 |
Ho-Su Lee1, Yumi Lee, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim.
Abstract
We describe a paradoxical response involving the central nervous system in a patient with steroid-refractory tuberculous meningitis that was unresponsive to systemic corticosteroids but was improved with adalimumab. The immunomodulatory effect of tumor necrosis factor inhibitors may have a role in replacing or enhancing the activity of steroids in the management of steroid-refractory tuberculous meningitis.Entities:
Mesh:
Substances:
Year: 2011 PMID: 22045163 DOI: 10.1007/s10156-011-0334-y
Source DB: PubMed Journal: J Infect Chemother ISSN: 1341-321X Impact factor: 2.211