| Literature DB >> 22044929 |
Tanushree Ganguly1, Benjamin B Kasten, Dejan-Krešimir Bučar, Leonard R MacGillivray, Clifford E Berkman, Paul D Benny.
Abstract
Facile reactivity of hydrazides and aldehydes was explored as potential coupling partners for incorporation into M(CO)(3) (M = Re, (99m)Tc) based radiopharmaceuticals. Both 'click, then chelate' and 'prelabel, then click' synthetic routes produced identical products in high yields and lacked metal-hydrazide/-hydrazone interactions, highlighting the potential of this click strategy. This journal is © The Royal Society of Chemistry 2011Entities:
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Year: 2011 PMID: 22044929 PMCID: PMC3236597 DOI: 10.1039/c1cc15451f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222