| Literature DB >> 22043921 |
Hidenori Kinoshita1, Tomoyuki Ishikawa, Katsukiyo Miura.
Abstract
The dialkylaluminum hydride-promoted reaction of 1-silylalk-3-en-1-ynes gave symmetrical 1,2,3,5-tetrasubstituted benzenes as single regioisomers. The novel cyclodimerization via skeletal rearrangement can be rationalized by an unprecedented mechanism involving sequential hydroalumination, alkene isomerization, carboalumination, carbon-carbon bond cleavage, and retro-hydroalumination.Entities:
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Year: 2011 PMID： 22043921 DOI： 10.1021/ol202601s
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005