Invasive Vibrio cholerae non-O1 non-0139 infection in a thalassemic child.

Invasive, extra-intestinal infection with Vibrio cholerae non-O1, non-O139 is rare especially among children. Herein the authors report a 12-year-old girl with underlying beta-thalassemia status post-splenectomy presenting with V. cholerae non-O1, non-O139 gastroenteritis with concomitant septicemia. The pathogen was identified from stool and blood culture and the patient recovered uneventfully after antimicrobial and supportive therapy. A review and comparison of clinical manifestations and outcomes with the previous four cases of invasive V. cholerae non-O1, non-O139 in postsplenectomy thalassemic pediatric patients is reported.