| Literature DB >> 22042320 |
Osamu Ohno1, Tatsuhiko Chiba, Seiji Todoroki, Hideaki Yoshimura, Norihito Maru, Ken Maekawa, Hiroshi Imagawa, Kaoru Yamada, Atsushi Wakamiya, Kiyotake Suenaga, Daisuke Uemura.
Abstract
Novel sesquiterpene alkaloids, halichonines A (1), B (2), and C (3), were identified from the marine sponge Halichondria okadai Kadota. By spectroscopic analyses and synthesis, their structures were revealed to include a 6,6-bicyclic ring system and two prenylated amine moieties. In addition, 2 induced apoptosis in HL60 human leukemia cells.Entities:
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Year: 2011 PMID： 22042320 DOI： 10.1039/c1cc15557a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222