R Ganesh1, L Janakiraman, B Meenakshi. 1. Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital and The CHILDS Trust Medical Research Foundation, 12A Nageswara Road, Chennai, India. ganeped79@ rediffmail.com
Abstract
AIM: To investigate serum zinc levels in children with simple febrile and epileptic seizures and compare them with controls. METHODS: A prospective, case-control study was conducted between July 2009 and September 2010 in Kanchi Kamakoti CHILDS Trust Hospital, Chennai. Sixty-seven children (22 with epileptic seizures, 23 with simple febrile seizures and 22 controls) were enrolled. Serum zinc level was estimated using atomic absorption spectrometry. RESULTS: Mean (SD) serum zinc level in children with epileptic seizures, simple febrile seizures and controls were 969·8 (177·3), 638·1 (206·8) and 939·9 (258·4) ug/L, respectively (p<0·05). CONCLUSION: Serum zinc levels are lower in children with febrile seizures than in those with epileptic seizures and normal children. Zinc supplementation of children at risk of febrile seizures requires further study.
AIM: To investigate serum zinc levels in children with simple febrile and epileptic seizures and compare them with controls. METHODS: A prospective, case-control study was conducted between July 2009 and September 2010 in Kanchi Kamakoti CHILDS Trust Hospital, Chennai. Sixty-seven children (22 with epileptic seizures, 23 with simple febrile seizures and 22 controls) were enrolled. Serum zinc level was estimated using atomic absorption spectrometry. RESULTS: Mean (SD) serum zinc level in children with epileptic seizures, simple febrile seizures and controls were 969·8 (177·3), 638·1 (206·8) and 939·9 (258·4) ug/L, respectively (p<0·05). CONCLUSION: Serum zinc levels are lower in children with febrile seizures than in those with epileptic seizures and normal children. Zinc supplementation of children at risk of febrile seizures requires further study.
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