Literature DB >> 22041236

Clinical outcome of laparoscopic and open colectomy for right colonic carcinoma.

J S Khan1, A K Hemandas, K G Flashman, A Senapati, D O'Leary, A Parvaiz.   

Abstract

INTRODUCTION: Laparoscopic colorectal surgery has gained widespread acceptance. While many studies have compared laparoscopic and open left-sided resections, there is limited literature on right colonic resections. We aimed to analyse the short-term outcome of laparoscopic (LRH) and open right hemicolectomy (ORH) in our unit.
METHODS: Consecutive patients undergoing elective right hemicolectomies over a period of 28 months were included in the study. No selection criteria were used to allocate the surgical approach. Study parameters included surgical technique, demographic details, ASA grade, body mass index (BMI), length of hospital stay (LOS), post-operative mortality and morbidity, readmission rate and histopathological data.
RESULTS: A total of 164 patients underwent right hemicolectomies during the study period (LRH: 89, ORH: 75). Both groups were comparable in age, sex, BMI, ASA grade, tumour stage and lymph node harvest. Four patients (4.5%) in the laparoscopic group required conversion to open surgery. In resections with curative intent, microscopic margins were positive in two patients (3%) in the ORH group compared with one (1%) in the LRH group. Seven ORH patients had an adverse post-operative outcome (three anastomotic leaks, four deaths); there were no deaths/immediate complications in the LRH group (p<0.05). The median LOS for LRH patients (4 days, range: 2-21 days) was significantly shorter than for ORH patients (8 days, range: 3-38 days) (p<0.0001, Mann-Whitney U test). By day 5, 77% of LRH patients were discharged compared with only 21% of patients in the ORH group. There were two readmissions (2.7%) in the ORH group and nine (10.1%) in the LRH group.
CONCLUSIONS: Our findings demonstrate advantages in favour of LRH in terms of a shorter hospital stay and reduced post-operative major complications. LRH is safe and should therefore be available to all patients requiring colonic resection.

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Year:  2011        PMID: 22041236      PMCID: PMC3566685          DOI: 10.1308/147870811X13137608455299

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  25 in total

1.  Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer.

Authors:  N S Abraham; J M Young; M J Solomon
Journal:  Br J Surg       Date:  2004-09       Impact factor: 6.939

2.  Minimally invasive colon resection (laparoscopic colectomy).

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Journal:  Lancet       Date:  1994-07-02       Impact factor: 79.321

4.  Do prior abdominal operations alter the outcome of laparoscopically assisted right hemicolectomy?

Authors:  C T Hamel; A J Pikarsky; E Weiss; J Nogueras; S D Wexner
Journal:  Surg Endosc       Date:  2000-09       Impact factor: 4.584

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Authors:  Antonio M Lacy; Juan C García-Valdecasas; Salvadora Delgado; Antoni Castells; Pilar Taurá; Josep M Piqué; Josep Visa
Journal:  Lancet       Date:  2002-06-29       Impact factor: 79.321

7.  The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer.

Authors:  Antonio M Lacy; Salvadora Delgado; Antoni Castells; Hubert A Prins; Vicente Arroyo; Ainitze Ibarzabal; Josep M Pique
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8.  A comparison of laparoscopically assisted and open colectomy for colon cancer.

Authors:  Heidi Nelson; Daniel J Sargent; H Sam Wieand; James Fleshman; Mehran Anvari; Steven J Stryker; Robert W Beart; Michael Hellinger; Richard Flanagan; Walter Peters; David Ota
Journal:  N Engl J Med       Date:  2004-05-13       Impact factor: 91.245

9.  Comparison between midline incision and limited right skin crease incision for right-sided colonic cancers.

Authors:  D Donati; S R Brown; K W Eu; Y H Ho; F Seow-Choen
Journal:  Tech Coloproctol       Date:  2002-04       Impact factor: 3.781

10.  Experience with laparoscopic colorectal surgery for malignant disease.

Authors:  P J Guillou; A Darzi; J R Monson
Journal:  Surg Oncol       Date:  1993       Impact factor: 3.279

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Review 1.  Laparoscopic right colectomy reduces short-term mortality and morbidity. Results of a systematic review and meta-analysis.

Authors:  Alberto Arezzo; Roberto Passera; Valentina Ferri; Federica Gonella; Roberto Cirocchi; Mario Morino
Journal:  Int J Colorectal Dis       Date:  2015-07-04       Impact factor: 2.571

Review 2.  Surgical approach to right colon cancer: From open technique to robot. State of art.

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Review 3.  Preoperative prediction of conversion from laparoscopic rectal resection to open surgery: a clinical study of conversion scoring of laparoscopic rectal resection to open surgery.

Authors:  Guang-Dong Zhang; Xu-Ting Zhi; Jian-Li Zhang; Guang-Bo Bu; Gang Ma; Kai-Lei Wang
Journal:  Int J Colorectal Dis       Date:  2015-06-16       Impact factor: 2.571

4.  Right colectomy from open to robotic - a single-center experience with functional outcomes in a learning-curve setting.

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Journal:  Langenbecks Arch Surg       Date:  2022-06-09       Impact factor: 3.445

5.  Tumour-associated macrophages correlate with microvascular bed extension in colorectal cancer patients.

Authors:  Ilaria Marech; Michele Ammendola; Rosario Sacco; Giuseppe Sammarco; Valeria Zuccalà; Nicola Zizzo; Christian Leporini; Maria Luposella; Rosa Patruno; Gianfranco Filippelli; Emilio Russo; Mariangela Porcelli; Cosmo Damiano Gadaleta; Giovambattista De Sarro; Girolamo Ranieri
Journal:  J Cell Mol Med       Date:  2016-04-22       Impact factor: 5.310

6.  Right hemicolectomy: a network meta-analysis comparing open, laparoscopic-assisted, total laparoscopic, and robotic approach.

Authors:  Emanuele Rausa; Michael Eamon Kelly; Emanuele Asti; Alberto Aiolfi; Gianluca Bonitta; Luigi Bonavina
Journal:  Surg Endosc       Date:  2018-11-19       Impact factor: 4.584

7.  Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy.

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Journal:  Oncol Lett       Date:  2013-08-02       Impact factor: 2.967

8.  Correlation between serum tryptase, mast cells positive to tryptase and microvascular density in colo-rectal cancer patients: possible biological-clinical significance.

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Journal:  PLoS One       Date:  2014-06-10       Impact factor: 3.240

9.  A cost-minimization analysis of first intention laparoscopic compared to open right hemicolectomy for colon cancer.

Authors:  Adam L Widdison; Victoria Barns; Oliver Prescott; Adam Pollard
Journal:  Ann Med Surg (Lond)       Date:  2015-11-19

10.  Procedural and post-operative complications associated with laparoscopic versus open abdominal surgery for right-sided colonic cancer resection: A systematic review and meta-analysis.

Authors:  Yong Sheng Li; Fan Chun Meng; Jun Kai Lin
Journal:  Medicine (Baltimore)       Date:  2020-10-02       Impact factor: 1.817

  10 in total

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