Literature DB >> 22040698

Immunity as a link between obesity and insulin resistance.

Nishan S Kalupahana1, Naima Moustaid-Moussa, Kate J Claycombe.   

Abstract

Obesity is a major public health problem in the United States and worldwide. Further, obesity is causally linked to the pathogenesis of insulin resistance, metabolic syndrome and type-2 diabetes (T2D). A chronic low-grade inflammation occurring in adipose tissue is at least in part responsible for the obesity-induced insulin resistance. This adipose tissue inflammation is characterized by changes in immune cell populations giving rise to altered adipo/cytokine profiles, which in turn induces skeletal muscle and hepatic insulin resistance. Detailed molecular mechanisms of insulin resistance, adipose tissue inflammation and the implications of these findings on therapeutic strategies are discussed in this review. Published by Elsevier Ltd.

Entities:  

Mesh：

Year:  2011        PMID： 22040698     DOI： 10.1016/j.mam.2011.10.011

Source DB:  PubMed          Journal:  Mol Aspects Med        ISSN： 0098-2997


  79 in total

1.  OX40 promotes obesity-induced adipose inflammation and insulin resistance.

Authors:  Bing Liu; Hengchi Yu; Guangyong Sun; Xiaojing Sun; Hua Jin; Chunpan Zhang; Wen Shi; Dan Tian; Kai Liu; Hufeng Xu; Xinmin Li; Jie Yin; Xu Hong; Dong Zhang
Journal:  Cell Mol Life Sci       Date:  2017-06-13       Impact factor: 9.261

Review 2.  Omega-3 fatty acids in obesity and metabolic syndrome: a mechanistic update.

Authors:  Kembra Albracht-Schulte; Nishan Sudheera Kalupahana; Latha Ramalingam; Shu Wang; Shaikh Mizanoor Rahman; Jacalyn Robert-McComb; Naima Moustaid-Moussa
Journal:  J Nutr Biochem       Date:  2018-02-27       Impact factor: 6.048

Review 3.  Exercise, Obesity, and Cutaneous Wound Healing: Evidence from Rodent and Human Studies.

Authors:  Brandt D Pence; Jeffrey A Woods
Journal:  Adv Wound Care (New Rochelle)       Date:  2014-01-01       Impact factor: 4.730

Review 4.  Macrophage-induced adipose tissue dysfunction and the preadipocyte: should I stay (and differentiate) or should I go?

Authors:  Alexander Sorisky; André S D Molgat; AnneMarie Gagnon
Journal:  Adv Nutr       Date:  2013-01-01       Impact factor: 8.701

Review 5.  The pathophysiology of hypertension in patients with obesity.

Authors:  Vincent G DeMarco; Annayya R Aroor; James R Sowers
Journal:  Nat Rev Endocrinol       Date:  2014-04-15       Impact factor: 43.330

6.  Six months of treatment with the endoscopic duodenal-jejunal bypass liner does not lead to decreased systemic inflammation in obese patients with type 2 diabetes.

Authors:  Charlotte de Jonge; Sander S Rensen; Hedwig M A D'Agnolo; Nicole D Bouvy; Wim A Buurman; Jan Willem M Greve
Journal:  Obes Surg       Date:  2014-02       Impact factor: 4.129

Review 7.  Targeting Islets: Metabolic Surgery Is More than a Bariatric Surgery.

Authors:  Xi Chen; Jingjing Zhang; Zhiguang Zhou
Journal:  Obes Surg       Date:  2019-09       Impact factor: 4.129

8.  Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice.

Authors:  Brian Bostick; Javad Habibi; Vincent G DeMarco; Guanghong Jia; Timothy L Domeier; Michelle D Lambert; Annayya R Aroor; Ravi Nistala; Shawn B Bender; Mona Garro; Melvin R Hayden; Lixin Ma; Camila Manrique; James R Sowers
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-03-06       Impact factor: 4.733

9.  Plasma Fatty Acid Composition and Estimated Desaturase Activities Reflect Dietary Patterns in Subjects with Metabolic Syndrome.

Authors:  N Pavithra; Priyanka S Bannikoppa; Sheila Uthappa; Anura V Kurpad; Indu Mani
Journal:  Indian J Clin Biochem       Date:  2017-07-22

Review 10.  N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome.

Authors:  Lindsay E Robinson; Vera C Mazurak
Journal:  Lipids       Date:  2013-03-01       Impact factor: 1.880
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