Literature DB >> 22040663

[Eosinophilic myocarditis and sudden unexpected death in a younger patient treated with antipsychotics].

Rikke Kjærgaard Christoffersen1, Lone Due Vestergård, Lene Høimark, Annie Vesterby.   

Abstract

A 36 year-old man suffering from schizophrenia was found dead in his apartment. Forensic autopsy was performed due to sudden unexpected death but did not yield the cause of death. Histological examination of the heart showed eosinophilic myocarditis (EM) while forensic chemistry showed a raised level of aripripazol. We discuss the risk of sudden cardiac death in patients receiving antipsychotic drugs and the possible connection between raised drug levels and EM, and we emphasise the importance of autopsy and hope for better means in the future of finding patients at risk.

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Year:  2011        PMID: 22040663

Source DB:  PubMed          Journal:  Ugeskr Laeger        ISSN: 0041-5782


  4 in total

Review 1.  The cardiac safety of aripiprazole treatment in patients at high risk for torsade: a systematic review with a meta-analytic approach.

Authors:  Christoffer Polcwiartek; Benjamin Sneider; Claus Graff; David Taylor; Jonathan Meyer; Jørgen K Kanters; Jimmi Nielsen
Journal:  Psychopharmacology (Berl)       Date:  2015-08-01       Impact factor: 4.530

2.  Eosinophilic myocarditis during treatment with olanzapine - report of two possible cases.

Authors:  Torkel Vang; Mary Rosenzweig; Christina Hedegaard Bruhn; Christoffer Polcwiartek; Jørgen Kim Kanters; Jimmi Nielsen
Journal:  BMC Psychiatry       Date:  2016-03-17       Impact factor: 3.630

3.  Association of antipsychotic use with raised eosinophil count.

Authors:  Konstantinos Tsamakis; Christoph Mueller; Ioannis Hortis; Maria Kallergi; Ioannis Tolos; Evangelos Alevyzakis; Nikolaos Siafakas; Andreas Ouranidis; Dimitrios Tsiptsios; Stylianos Kympouropoulos; Demetrios A Spandidos; Nikolaos Smyrnis; Emmanouil Rizos
Journal:  Exp Ther Med       Date:  2021-03-19       Impact factor: 2.447

4.  Case report of eosinophilia induced by quetiapine.

Authors:  Liming Chen; Pei Tan; Xiaolin Tan
Journal:  Shanghai Arch Psychiatry       Date:  2015-12-25
  4 in total

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