Literature DB >> 22040289

Is a routine voiding cystourethrogram necessary in children after the first febrile urinary tract infection?

Jun Ho Lee1, Moon Kyu Kim, Sung Eun Park.   

Abstract

AIM: The aim of this study was to estimate the value of identifying vesicoureteral reflux (VUR) on a voiding cystourethrogram (VCUG) and the benefit of VUR management according to imaging strategies at the first febrile urinary tract infection (UTI).
METHODS: Children aged 1-144 months (n = 618) with the first febrile UTI admitted at our hospital from 2000 to 2009 were enrolled. In all patients, renal sonogram (US), (99m) Tc-dimercaptosuccinic acid (DMSA) renal scanning and VCUG were performed. Retrospective analyses per patient and per renal unit were performed.
RESULTS: Abnormal US or DMSA scans had a sensitivity of 100% and a negative predictive value (NPV) of 100% to detect high-grade reflux. In hydronephrotic kidneys, DMSA scanning had a sensitivity of 88.2% and a NPV of 97.1% to detect high-grade reflux.
CONCLUSION: Routine VCUG is not required after the first febrile UTI in patients with normal US or normal DMSA scan. Even if the US reveals hydronephrosis, routine VCUG is not necessary if the DMSA findings are normal. It is recommended that children who did not receive both a DMSA scan and VCUG after the first febrile UTI should be followed up over the long term.
© 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

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Year:  2011        PMID: 22040289     DOI: 10.1111/j.1651-2227.2011.02507.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  10 in total

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2.  History of recurrent urinary tract infection is not predictive of abnormality on voiding cystourethrogram.

Authors:  Ariella A Friedman; Cortney Wolfe-Christensen; Amanda Toffoli; David E Hochsztein; Jack S Elder; Yegappan Lakshmanan
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Review 6.  Dimercaptosuccinic acid scan or ultrasound in screening for vesicoureteral reflux among children with urinary tract infections.

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8.  Reconsideration of urine culture for the diagnosis of acute pyelonephritis in children: a new challenging method for diagnosing acute pyelonephritis.

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9.  Abnormal dimercaptosuccinic Acid scan may be related to persistence of vesicoureteral reflux in children with febrile urinary tract infection.

Authors:  Hyun Chong Ki; Sun-Ouck Kim; Dong Hun Yoo; In Sang Hwang; Eu Chang Hwang; Kyung Jin Oh; Seung Il Jung; Taek Won Kang; Dongdeuk Kwon; Kwangsung Park; Soo Bang Ryu
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10.  Prediction of Cortical Defect Using C-Reactive Protein and Urine Sodium to Potassium Ratio in Infants with Febrile Urinary Tract Infection.

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  10 in total

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