| Literature DB >> 22040193 |
Benjamin I Goldstein1, Katelyn A Collinger, Francis Lotrich, Anna L Marsland, Mary-Kay Gill, David A Axelson, Boris Birmaher.
Abstract
Mood symptoms in adult bipolar disorder are associated with increased proinflammatory markers and decreased brain-derived neurotrophic factor (BDNF). We examined serum interleukin-6, high-sensitivity C-reactive protein (hsCRP), and BDNF among 30 bipolar disorder adolescents. Hypomanic/manic symptoms were positively associated with hsCRP. BDNF levels were negatively associated with interleukin-6. Forty percent had cardiovascular high-risk hsCRP levels. Larger longitudinal studies are warranted.Entities:
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Year: 2011 PMID: 22040193 PMCID: PMC3205790 DOI: 10.1089/cap.2011.0009
Source DB: PubMed Journal: J Child Adolesc Psychopharmacol ISSN: 1044-5463 Impact factor: 2.576