Literature DB >> 22038752

An analysis of vascular surgery in elderly patients to determine whether age affects treatment strategy.

G O'Brien1, Z Martin, N Haider, M Colgan, S O'Neill, D Moore, P Madhavan.   

Abstract

OBJECTIVES: The incidence of arterial disease increases with age. Increasing life expectancy in the western world will intensify demands on vascular surgeons with regard to increasing caseload, expanding patient selection criteria, and more complex and minimally-invasive treatment options. We analysed our arterial cases over the past 31 years (n = 6,144) and compared our methods of intervention and complication rates in the elderly population (>75) with the younger cohort, in order to determine whether age should influence our management strategies.
METHODS: Data were collected prospectively on all arterial cases from 1978 to 2009. Methods of intervention and corresponding complication rates in the over and under 75-year-old cohorts were analyzed utilizing Fisher's exact test to calculate two-sided p values, relative risks and 95% confidence intervals.
RESULTS: Endovascular management has evolved to become the first line approach for all arterial cases (except carotid disease). Age was a significant risk factor for death and MI for the open procedures of AAA repair (p = 0.049 and p = 0.007, respectively), aorto-bifemoral reconstruction (p < 0.0001 and p = 0.006) and lower limb bypass (p = 0.01 and p < 0.001). For endovascular procedures, age did not impact on MI rate for EVAR (p = 0.78) or death rates for EVAR (p = 0.46), iliac angioplasty (p = 0.62) or lower limb angioplasty (p = 0.29).
CONCLUSION: A paradigm shift has occurred towards endovascular management of aortic, iliac and femoral arterial disease. Whilst patient age >75 significantly impacts on complication rates from index open vascular procedures, age does not impact upon complication rates of corresponding endovascular procedures. We, therefore, recommend an endovascular approach be adopted as first line for all patients, regardless of patient age.

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Year:  2011        PMID: 22038752     DOI: 10.1007/s11845-011-0779-0

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  20 in total

1.  ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery---executive summary a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery).

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Review 2.  Statins for the prevention of perioperative cardiovascular complications in vascular surgery.

Authors:  Olaf Schouten; Jeroen J Bax; Martin Dunkelgrun; Harm H Feringa; Hero van Urk; Don Poldermans
Journal:  J Vasc Surg       Date:  2006-08       Impact factor: 4.268

Review 3.  [Vascular surgery in the elderly].

Authors:  D Böckler; H Schumacher; J-R Allenberg
Journal:  Chirurg       Date:  2005-02       Impact factor: 0.955

4.  Carotid endarterectomy in octogenarians: comparison with patient characteristics and outcomes in younger patients.

Authors:  J R Schneider; J S Droste; N Schindler; J F Golan
Journal:  J Vasc Surg       Date:  2000-05       Impact factor: 4.268

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Journal:  N Engl J Med       Date:  1980-06-12       Impact factor: 91.245

Review 6.  The epidemiology of peripheral arterial disease: importance of identifying the population at risk.

Authors:  M H Criqui; J O Denenberg; R D Langer; A Fronek
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7.  Results of carotid surgery in elderly patients.

Authors:  Y Kerdiles; A Lucas; L Podeur; P Ferte; A Cardon
Journal:  J Cardiovasc Surg (Torino)       Date:  1997-08       Impact factor: 1.888

8.  Revascularization for chronic critical lower limb ischemia in octogenarians is worthwhile.

Authors:  Philippe Brosi; Florian Dick; Dai Do Do; Juerg Schmidli; Iris Baumgartner; Nicolas Diehm
Journal:  J Vasc Surg       Date:  2007-12       Impact factor: 4.268

9.  Comparative results of open lower extremity revascularization in nonagenarians.

Authors:  Jeffrey Hnath; Sean P Roddy; R Clement Darling; Philip S K Paty; John B Taggert; Manish Mehta
Journal:  J Vasc Surg       Date:  2009-06       Impact factor: 4.268

10.  Open abdominal aortic aneurysm repair in octogenarians before and after the adoption of endovascular grafting procedures.

Authors:  Enzo Ballotta; Giuseppe Da Giau; Alessio Bridda; Mario Gruppo; Alberto Pauletto; Bruno Martella
Journal:  J Vasc Surg       Date:  2007-12-03       Impact factor: 4.268

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  1 in total

1.  Incidence of Myocardial Infarction After High-Risk Vascular Operations in Adults.

Authors:  Yen-Yi Juo; Aditya Mantha; Ramin Ebrahimi; Boback Ziaeian; Peyman Benharash
Journal:  JAMA Surg       Date:  2017-11-15       Impact factor: 14.766

  1 in total

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