Literature DB >> 22038270

Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial.

Rebecca Schennach1, Michael Riedel, Michael Obermeier, Markus Jäger, Max Schmauss, Gerd Laux, Herbert Pfeiffer, Dieter Naber, Lutz G Schmidt, Wolfgang Gaebel, Joachim Klosterkötter, Isabella Heuser, Wolfgang Maier, Matthias R Lemke, Eckart Rüther, Stefan Klingberg, Markus Gastpar, Florian Seemüller, Hans-Jürgen Möller.   

Abstract

Remission and recovery are major outcome goals in schizophrenia yet their predictors have not been studied in detail. Therefore, 186 patients were examined regarding remission and recovery including their potential sociodemographic and clinical predictors 1 year after discharge. Remission was defined according to the consensus remission criteria and recovery following the definition by Liberman et al. (2002). Of the 186 patients 54% achieved remission and 26% recovery at the 1-year follow-up. The remission status at discharge was found to significantly influence remission and recovery at follow-up. A higher SOFAS score (P = 0.0002) as well as a positive attitude towards treatment at discharge (P = 0.0038) were identified to be significant predictors of remission at 1-year follow-up. Having a job (P = <0.0001) and being without pharmacological treatment at follow-up (P = 0.0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome.

Entities:  

Mesh:

Year:  2012        PMID: 22038270     DOI: 10.1007/s11126-011-9193-z

Source DB:  PubMed          Journal:  Psychiatr Q        ISSN: 0033-2720


  19 in total

1.  Case history data and prognosis in schizophrenia.

Authors:  L PHILLIPS
Journal:  J Nerv Ment Dis       Date:  1953-06       Impact factor: 2.254

2.  Rates and predictors of remission and recovery during 3 years in 392 never-treated patients with schizophrenia.

Authors:  M Lambert; D Naber; A Schacht; T Wagner; H-P Hundemer; A Karow; C G Huber; D Suarez; J M Haro; D Novick; R W Dittmann; B G Schimmelmann
Journal:  Acta Psychiatr Scand       Date:  2008-09       Impact factor: 6.392

Review 3.  Definitions of the term 'recovered' in schizophrenia and other disorders.

Authors:  Ann Faerden; Ragnar Nesvåg; Stephen R Marder
Journal:  Psychopathology       Date:  2008-07-01       Impact factor: 1.944

Review 4.  Who needs antipsychotic medication in the earliest stages of psychosis? A reconsideration of benefits, risks, neurobiology and ethics in the era of early intervention.

Authors:  S M Francey; B Nelson; A Thompson; A G Parker; M Kerr; C Macneil; R Fraser; F Hughes; K Crisp; S Harrigan; S J Wood; M Berk; P D McGorry
Journal:  Schizophr Res       Date:  2010-03-26       Impact factor: 4.939

5.  Reliability and validity of the positive and negative syndrome scale for schizophrenics.

Authors:  S R Kay; L A Opler; J P Lindenmayer
Journal:  Psychiatry Res       Date:  1988-01       Impact factor: 3.222

6.  A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables.

Authors:  D Naber
Journal:  Int Clin Psychopharmacol       Date:  1995-09       Impact factor: 1.659

Review 7.  Remission in schizophrenia: proposed criteria and rationale for consensus.

Authors:  Nancy C Andreasen; William T Carpenter; John M Kane; Robert A Lasser; Stephen R Marder; Daniel R Weinberger
Journal:  Am J Psychiatry       Date:  2005-03       Impact factor: 18.112

8.  Recovery in the outpatient setting: 36-month results from the Schizophrenia Outpatients Health Outcomes (SOHO) study.

Authors:  Diego Novick; Josep Maria Haro; David Suarez; Eduard Vieta; Dieter Naber
Journal:  Schizophr Res       Date:  2008-12-13       Impact factor: 4.939

9.  Scientific and consumer models of recovery in schizophrenia: concordance, contrasts, and implications.

Authors:  Alan S Bellack
Journal:  Schizophr Bull       Date:  2006-02-03       Impact factor: 9.306

10.  Symptomatic remission and social/vocational functioning in outpatients with schizophrenia: prevalence and associations in a cross-sectional study.

Authors:  Luis San; Antonio Ciudad; Enrique Alvarez; Julio Bobes; Inmaculada Gilaberte
Journal:  Eur Psychiatry       Date:  2007-09-27       Impact factor: 5.361

View more
  5 in total

1.  Predictors and Prevalence of Recovery and Remission for Consumers Discharged from Mental Hospitals in a Chinese Society.

Authors:  Daniel K W Young; Petrus Y N Ng; Jiayan Pan
Journal:  Psychiatr Q       Date:  2017-12

Review 2.  Functional outcomes in schizophrenia: employment status as a metric of treatment outcome.

Authors:  Rebecca Schennach; Richard Musil; Hans-Jürgen Möller; Michael Riedel
Journal:  Curr Psychiatry Rep       Date:  2012-06       Impact factor: 5.285

3.  Embracing Psychosis: A Cognitive Insight Intervention Improves Personal Narratives and Meaning-Making in Patients With Schizophrenia.

Authors:  Steffen Moritz; Candelaria I Mahlke; Stefan Westermann; Friederike Ruppelt; Paul H Lysaker; Thomas Bock; Christina Andreou
Journal:  Schizophr Bull       Date:  2018-02-15       Impact factor: 9.306

4.  Predictors of vocational status in schizophrenia patients--Results from the Polish nationwide survey.

Authors:  Andrzej Kiejna; Patryk Piotrowski; Błażej Misiak; Tomasz Adamowski; Agata Schubert; Iwona Skrzekowska-Baran; Dorota Frydecka
Journal:  Int J Soc Psychiatry       Date:  2015-04-02

5.  The Association of Social Support and Symptomatic Remission among Community-Dwelling Schizophrenia Patients: A Cross-Sectional Study.

Authors:  Chi-Hsuan Fan; Shih-Chieh Hsu; Fei-Hsiu Hsiao; Chia-Ming Chang; Chia-Yih Liu; Yu-Ming Lai; Yu-Ting Chen
Journal:  Int J Environ Res Public Health       Date:  2021-04-09       Impact factor: 3.390

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.