Literature DB >> 22037567

Polyprenylated isoflavanone and isoflavonoids from Ormosia henryi and their cytotoxicity and anti-oxidation activity.

Shixiu Feng1, Jing Hao, Zhifang Xu, Tao Chen, Samuel X Shengxiang Qiu.   

Abstract

A rare naturally-occurring polyprenylated isoflavanone, designated ormosinol (1), and a new isoflavonoid glycoside, named ormosinoside (2), along with 21 known compounds were isolated from the root bark of Ormosia henryi Prain. The structures of compounds 1 and 2 were determined as 5,7,2',4'-tetrahydroxyl-6,8,5'-tri-(γ,γ-dimethylallyl)isoflavanone and isoprunetin-7-O-β-D-xylopyranosyl-(1 → 6)-β-D-glucopyranoside on the basis of a combination of 1D-, 2D-NMR and mass spectroscopic measurements. Compound 1 showed significant anti-oxidation activity against DPPH radicals (IC(50) 28.5 μM) and cancer cell line (A549, LAC, and HepG2) growth inhibitory activity with IC(50) ranging from 4.25 to 7.09 μM, while compound 2 found to be inactive to both testing systems.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 22037567     DOI： 10.1016/j.fitote.2011.10.007

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  6 in total

1.  Genista sessilifolia DC. extracts induce apoptosis across a range of cancer cell lines.

Authors:  P Bontempo; D Rigano; A Doto; C Formisano; M Conte; A Nebbioso; V Carafa; G Caserta; V Sica; A M Molinari; L Altucci
Journal:  Cell Prolif       Date:  2013-04       Impact factor: 6.831

2.  Plant-derived bioactive compounds produced by Streptomyces variabilis LCP18 associated with Litsea cubeba (Lour.) Pers as potential target to combat human pathogenic bacteria and human cancer cell lines.

Authors:  Ngoc Tung Quach; Quang Huy Nguyen; Thi Hanh Nguyen Vu; Thi Thu Hang Le; Thi Thu Thuy Ta; Tien Dat Nguyen; Thuoc Van Doan; The Van Nguyen; Tat Thanh Dang; Xuan Canh Nguyen; Hoang Ha Chu; Quyet Tien Phi
Journal:  Braz J Microbiol       Date:  2021-05-01       Impact factor: 2.476

3.  Estrogenic and cytotoxic potentials of compounds isolated from Millettia macrophylla Benth (Fabaceae): towards a better understanding of its underlying mechanisms.

Authors:  Stéphane Zingue; Job Tchoumtchoua; Dieudonnée Mireille Ntsa; Louis Pergaud Sandjo; Julia Cisilotto; Chantal Beatrice Magne Nde; Evelyn Winter; Charline Florence Awounfack; Derek Tantoh Ndinteh; Colin Clyne; Dieudonné Njamen; Maria Halabalaki; Tânia Beatriz Creczynski-Pasa
Journal:  BMC Complement Altern Med       Date:  2016-10-26       Impact factor: 3.659

Review 4.  Natural Products from Chinese Medicines with Potential Benefits to Bone Health.

Authors:  Chun-Tao Che; Man Sau Wong; Christopher Wai Kei Lam
Journal:  Molecules       Date:  2016-02-27       Impact factor: 4.411

5.  In Vitro and In Silico Potential Inhibitory Effects of New Biflavonoids from Ochna rhizomatosa on HIV-1 Integrase and Plasmodium falciparum.

Authors:  Angélique Nicolas Messi; Susan Lucia Bonnet; Brice Ayissi Owona; Anke Wilhelm; Eutrophe Le Doux Kamto; Joseph Thierry Ndongo; Xavier Siwe-Noundou; Madan Poka; Patrick H Demana; Rui W M Krause; Joséphine Ngo Mbing; Dieudonné Emmanuel Pegnyemb; Christian G Bochet
Journal:  Pharmaceutics       Date:  2022-08-15       Impact factor: 6.525

6.  In Vitro Antiplasmodial and Cytotoxic Activities of Compounds from the Roots of Eriosema montanum Baker f. (Fabaceae).

Authors:  Jean Claude Didelot Tomani; Olivier Bonnet; Alain Nyirimigabo; William Deschamps; Alembert Tiabou Tchinda; Olivia Jansen; Allison Ledoux; Marie Jeanne Mukazayire; Luc Vanhamme; Michel Frédérich; Raymond Muganga; Jacob Souopgui
Journal:  Molecules       Date:  2021-05-10       Impact factor: 4.411
  6 in total

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