| Literature DB >> 22036906 |
Ernesto A Salegio1, Lluis Samaranch, Adrian P Kells, John Forsayeth, Krystof Bankiewicz.
Abstract
In this review, we discuss recent developments in the delivery of adeno-associated virus-based vectors (AAV), particularly with respect to the role of axonal transport in vector distribution in the brain. The use of MRI-guidance and new stereotactic aiming devices have now established a strong foundation for neurological gene therapy to become an accepted procedure in interventional neurology.Entities:
Mesh:
Year: 2011 PMID: 22036906 PMCID: PMC3279613 DOI: 10.1016/j.addr.2011.10.005
Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN: 0169-409X Impact factor: 15.470