INTRODUCTION: Depressive and anxiety disorders often involve a chronic course. This study examined whether objective physical function is a predictor for the persistence of depressive and anxiety disorders. METHOD: The study sample consisted of 1206 persons with depressive and anxiety disorders at baseline. Hand grip strength and lung function were used as objective physical function measurements and were determined at baseline. Outcome variable was a 6-month depressive and/or anxiety diagnosis after 2 years of follow-up. RESULTS: Lower hand grip strength predicted the persistence of depressive and/or anxiety disorders at 2-year follow-up (per SD increase: OR=0.82, CI: 0.69-0.99, p=0.04). Associations were consistent for depressive and anxiety disorder persistence. Poorer lung function was associated with the persistence of depressive disorders (per SD increase: OR=0.83, CI: 0.70-0.98, p=0.03) but not with anxiety disorders. LIMITATIONS: Follow-up was limited to 2 years. CONCLUSIONS: Objectively measured poorer physical function predicted the persistence of depressive and/or anxiety disorders.
INTRODUCTION: Depressive and anxiety disorders often involve a chronic course. This study examined whether objective physical function is a predictor for the persistence of depressive and anxiety disorders. METHOD: The study sample consisted of 1206 persons with depressive and anxiety disorders at baseline. Hand grip strength and lung function were used as objective physical function measurements and were determined at baseline. Outcome variable was a 6-month depressive and/or anxiety diagnosis after 2 years of follow-up. RESULTS: Lower hand grip strength predicted the persistence of depressive and/or anxiety disorders at 2-year follow-up (per SD increase: OR=0.82, CI: 0.69-0.99, p=0.04). Associations were consistent for depressive and anxiety disorder persistence. Poorer lung function was associated with the persistence of depressive disorders (per SD increase: OR=0.83, CI: 0.70-0.98, p=0.03) but not with anxiety disorders. LIMITATIONS: Follow-up was limited to 2 years. CONCLUSIONS: Objectively measured poorer physical function predicted the persistence of depressive and/or anxiety disorders.
Authors: S Córdoba-Torrecilla; V A Aparicio; A Soriano-Maldonado; F Estévez-López; V Segura-Jiménez; I Álvarez-Gallardo; P Femia; M Delgado-Fernández Journal: Qual Life Res Date: 2015-09-08 Impact factor: 4.147
Authors: Verónica Cabanas-Sánchez; Irene Esteban-Cornejo; Solange Parra-Soto; Fanny Petermann-Rocha; Stuart R Gray; Fernando Rodríguez-Artalejo; Frederick K Ho; Jill P Pell; David Martínez-Gómez; Carlos Celis-Morales Journal: J Cachexia Sarcopenia Muscle Date: 2022-06-08 Impact factor: 12.063
Authors: Inge Petersen; Nancy L Pedersen; Taina Rantanen; William S Kremen; Wendy Johnson; Matthew S Panizzon; Lene Christiansen; Carol E Franz; Matt McGue; Kaare Christensen; Nayla R Hamdi; Robert F Krueger; Chandra Reynolds Journal: Behav Genet Date: 2015-08-29 Impact factor: 2.805