Literature DB >> 22032193

Transcriptional repressors: shutting off gene expression at the source affects developmental dynamics.

David N Arnosti1.   

Abstract

Developmental networks feature genes interlinked by transcriptional activation and repression. A new study indicates that repressors can 'shut the door' to newly initiating polymerases, allowing longer target genes to produce latent transcripts after shorter genes have been effectively silenced.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22032193     DOI： 10.1016/j.cub.2011.09.022

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  2 in total

1.  Complex cis-regulatory landscape of the insulin receptor gene underlies the broad expression of a central signaling regulator.

Authors:  Yiliang Wei; Rewatee H Gokhale; Anne Sonnenschein; Kelly Mone't Montgomery; Andrew Ingersoll; David N Arnosti
Journal:  Development       Date:  2016-10-01       Impact factor: 6.868

2.  Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancer.

Authors:  Arnar Palsson; Natalia Wesolowska; Sigrún Reynisdóttir; Michael Z Ludwig; Martin Kreitman
Journal:  PLoS One       Date:  2014-05-01       Impact factor: 3.240
  2 in total

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