Literature DB >> 22030170

[Clinical and ossification outcome of custom-made hydroxyapatite prothese for large skull defect].

H Hardy1, E Tollard, S Derrey, P Delcampe, J-M Péron, P Fréger, F Proust.   

Abstract

OBJECTIVE: Cranioplasty is an everyday concern in neurosurgery, especially in decompressive craniectomy cases. Our surgical team uses custom-made hydroxyapatite implants for large and/or complex defects. PATIENTS AND
METHOD: Eight patients had a custom-made prosthesis. Each of them has been reviewed by an independent observer. Each patient described his feeling of satisfaction, using a questionnaire, graduated from "A" (really satisfied) to "D" (unsatisfied). Each of them also underwent a CT-scan (helicoidal acquisition, 0.6mm thick for multiplanar reconstruction) to evaluate qualitatively the ossification graduated from "0" (no ossification) to "5" (continuous ossification). Maximal under-prosthetic bone thickness, intra-prosthetic calcic density were also reported.
RESULTS: Supervision delay was 43.7 months [6-99 months], average defect surface was 85.5 cm(2) [27.6-137.6 cm(2)], the craniectomy etiologies were intracranial hypertension (seven patients) and calvarial invasion (one patient). Implant tolerance was reparted in "A" score (50%) and "B" score (50%). Concerning ossification, six patients (75%) had a score of "2" or less and two patients had a score of "3" or "4". DISCUSSION: Hydroxyapatite custom-made implants for cranioplasty appear to be ideal for good aesthetic and tolerance results, but their ossification is hardly analyzed due to the prosthesis density higher than the bone's density. This is why we recommend them for children and in cases of complex defects such as pterion location.
Copyright © 2011. Published by Elsevier Masson SAS.

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Year:  2011        PMID: 22030170     DOI: 10.1016/j.neuchi.2011.09.006

Source DB:  PubMed          Journal:  Neurochirurgie        ISSN: 0028-3770            Impact factor:   1.553


  5 in total

1.  Custom-made hydroxyapatite for cranial repair in a specific pediatric age group (7-13 years old): a multicenter post-marketing surveillance study.

Authors:  Paolo Frassanito; Luca Massimi; Gianpiero Tamburrini; Federico Bianchi; Angelo Nataloni; Valentina Canella; Massimo Caldarelli
Journal:  Childs Nerv Syst       Date:  2018-07-10       Impact factor: 1.475

Review 2.  From Reparative Surgery to Regenerative Surgery: State of the Art of Porous Hydroxyapatite in Cranioplasty.

Authors:  Ismail Zaed; Andrea Cardia; Roberto Stefini
Journal:  Int J Mol Sci       Date:  2022-05-13       Impact factor: 6.208

3.  Hydroxyapatite ceramic implants for cranioplasty in children: a retrospective evaluation of clinical outcome and osteointegration.

Authors:  Pietro Spennato; Valentina Canella; Ferdinado Aliberti; Carmela Russo; Claudio Ruggiero; Angelo Nataloni; Milena Lombardo; Giuseppe Cinalli
Journal:  Childs Nerv Syst       Date:  2019-11-30       Impact factor: 1.475

4.  Use of "custom made" porous hydroxyapatite implants for cranioplasty: postoperative analysis of complications in 1549 patients.

Authors:  Roberto Stefini; Giacomo Esposito; Bruno Zanotti; Corrado Iaccarino; Marco Maria Fontanella; Franco Servadei
Journal:  Surg Neurol Int       Date:  2013-01-28

5.  Shape modifications of porous hydroxyapatite prostheses to improve rigid implant fixation: Experience in 12 cases.

Authors:  Alessandro Di Rienzo; Maurizio Iacoangeli; Lucia G M di Somma; Lorenzo Alvaro; Niccolò Nocchi; Massimo Scerrati
Journal:  Surg Neurol Int       Date:  2012-12-26
  5 in total

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