Literature DB >> 22029515

New approaches to the inhibition of replication of viral pathogens.

Anil Kumar1, Peter S Silverstein.   

Abstract

This meeting was a special symposium sponsored by the American Society for Biochemistry and Molecular Biology. The conference was held in Gangzhou, China on 24-26 July 2011 and shared a venue with the Society of Chinese Bioscientists in America Thirteenth International Symposium. Over 150 participants from the Americas, Europe, Asia and Australia attended the meeting. This article focuses on two areas of research in which there have been exciting developments that have application to the development of antivirals: the regulation of host and viral mRNA by RNAi and NF-κB regulation of viral gene expression.

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Year:  2011        PMID: 22029515      PMCID: PMC4090758          DOI: 10.1586/eri.11.114

Source DB:  PubMed          Journal:  Expert Rev Anti Infect Ther        ISSN: 1478-7210            Impact factor:   5.091


  12 in total

1.  Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.

Authors:  Benjamin P Lewis; Christopher B Burge; David P Bartel
Journal:  Cell       Date:  2005-01-14       Impact factor: 41.582

2.  High clade C HIV-1 viremia: how did we get here and where are we going?

Authors:  Myron S Cohen; Joseph Eron; Kelly Soderberg; Andrew McMichael
Journal:  AIDS       Date:  2011-07-31       Impact factor: 4.177

3.  Identification of small molecules that suppress microRNA function and reverse tumorigenesis.

Authors:  Koichi Watashi; Man Lung Yeung; Matthew F Starost; Ramachandra S Hosmane; Kuan-Teh Jeang
Journal:  J Biol Chem       Date:  2010-06-07       Impact factor: 5.157

4.  Kaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppression.

Authors:  Jeong-Gu Kang; Natalia Pripuzova; Vladimir Majerciak; Michael Kruhlak; Shu-Yun Le; Zhi-Ming Zheng
Journal:  J Virol       Date:  2011-01-05       Impact factor: 5.103

5.  The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis.

Authors:  Jing Fu; Zhaoxia Qu; Pengrong Yan; Chie Ishikawa; Rami I Aqeilan; Arnold B Rabson; Gutian Xiao
Journal:  Blood       Date:  2010-11-29       Impact factor: 22.113

6.  HIV-1 clade promoters strongly influence spatial and temporal dynamics of viral replication in vivo.

Authors:  Mireille Centlivre; Peter Sommer; Marie Michel; Raphaël Ho Tsong Fang; Sandrine Gofflo; Jenny Valladeau; Nathalie Schmitt; Françoise Thierry; Bruno Hurtrel; Simon Wain-Hobson; Monica Sala
Journal:  J Clin Invest       Date:  2005-02       Impact factor: 14.808

7.  Anticipating and blocking HIV-1 escape by second generation antiviral shRNAs.

Authors:  Nick C T Schopman; Olivier ter Brake; Ben Berkhout
Journal:  Retrovirology       Date:  2010-06-08       Impact factor: 4.602

8.  Human immunodeficiency virus type 1 escape is restricted when conserved genome sequences are targeted by RNA interference.

Authors:  Karin Jasmijn von Eije; Olivier ter Brake; Ben Berkhout
Journal:  J Virol       Date:  2007-12-12       Impact factor: 5.103

9.  Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1.

Authors:  Man Lung Yeung; Jun-ichirou Yasunaga; Yamina Bennasser; Nelson Dusetti; David Harris; Nafees Ahmad; Masao Matsuoka; Kuan-Teh Jeang
Journal:  Cancer Res       Date:  2008-11-01       Impact factor: 12.701

10.  Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes.

Authors:  Jialing Huang; Fengxiang Wang; Elias Argyris; Keyang Chen; Zhihui Liang; Heng Tian; Wenlin Huang; Kathleen Squires; Gwen Verlinghieri; Hui Zhang
Journal:  Nat Med       Date:  2007-09-30       Impact factor: 53.440

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