| Literature DB >> 22028582 |
Jeong-Hwan Yun1, Hong-Kyu Kang, So-Young Na, Joo-Young Roh, Jong-Rok Lee.
Abstract
Eccrine angiomatous hamartoma (EAH) is a rare benign disease that is characterized by an abnormal proliferation of eccrine glands and vascular elements. It is generally congenital, but it can appear before puberty. It usually presents as a single plaque or nodule, but multiple patch-like lesions are also possible. EAH is mostly asymptomatic, but it is sometimes associated with pain or hyperhidrosis. It generally does not require aggressive treatment, but the lesion can be excised due to pain, enlargement and cosmetic reasons. A 3-week-old Korean female presented with a hemorrhagic skin lesion on the right foot since birth. There was no specific birth history. The lesion first appeared on the third toe of the right foot and quickly spread to almost half of the right foot. Histopathology examination revealed acanthosis in the epidermis and a proliferation of eccrine ducts, glands and capillaries. The eccrine glands were immunohistochemically-positive for carcinoembryonic antigen.Entities:
Keywords: Eccrine glands; Hamartoma
Year: 2011 PMID: 22028582 PMCID: PMC3199432 DOI: 10.5021/ad.2011.23.S1.S84
Source DB: PubMed Journal: Ann Dermatol ISSN: 1013-9087 Impact factor: 1.444