| Literature DB >> 22028438 |
Norma I Rallón1, Judit Morello, Pablo Labarga, José M Benito, Sonia Rodríguez-Nóvoa, Eugenia Vispo, Pablo Barreiro, M Ángeles Castro, Koldo Aguirrebengoa, Juan A Pineda, P Miralles, M Jesús Tellez, Joaquín Portu, Celia Miralles, Antonio Ocampo, Vincent Soriano.
Abstract
The role of rs1127354/rs7270101 alleles at the inosine triphosphatase (ITPA) gene on ribavirin-induced anemia was assessed in 74 patients with hepatitis C virus and human immunodeficiency virus coinfection. Anemia developed in 80% of patients with normal ITPA activity compared with 33% of those with reduced ITPA activity. In contrast, ITPA variants did not influence sustained virological response.Entities:
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Year: 2011 PMID： 22028438 DOI： 10.1093/cid/cir665
Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079