Literature DB >> 22027866

Combining two-directional synthesis and tandem reactions: a short formal synthesis of halichlorine.

Camille Gignoux1, Annabella F Newton, Alexandre Barthelme, William Lewis, Marie-Lyne Alcaraz, Robert A Stockman.   

Abstract

A short and efficient synthesis of an advanced intermediate (1) in the Clive route to halichlorine has been achieved in 12 steps and 13.2% yield by a combined two-directional synthesis/tandem reaction strategy.

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Year:  2011        PMID: 22027866     DOI: 10.1039/c1ob06380d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds.

Authors:  Kieron M G O'Connell; Monica Díaz-Gavilán; Warren R J D Galloway; David R Spring
Journal:  Beilstein J Org Chem       Date:  2012-06-06       Impact factor: 2.883

  1 in total

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