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Literature DB >> 22027566

Brain-gut axis: from basic understanding to treatment of IBS and related disorders.

Abstract

The present review describes advances in understanding the mechanisms and provide an update of present and promising therapy directed at the gut or the brain in the treatment of irritable bowel syndrome (IBS). The diagnosis of IBS typically is based on identification of symptoms, such as the Rome III criteria for IBS in adults and children. The criteria are similar in children and adults. The focus of the present review is the bowel dysfunction associated with IBS.

Entities: Chemical Disease Gene Species

Mesh：

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Year: 2012 PMID： 22027566 PMCID： PMC3294167 DOI： 10.1097/MPG.0b013e31823d34c3

Source DB: PubMed Journal: J Pediatr Gastroenterol Nutr ISSN： 0277-2116 Impact factor: 2.839

113 in total

Review 1. Chronic constipation.

Authors: Anthony Lembo; Michael Camilleri
Journal: N Engl J Med Date: 2003-10-02 Impact factor: 91.245

Review 2. A systematic review of neuroimaging data during visceral stimulation.

Authors: Stuart W G Derbyshire
Journal: Am J Gastroenterol Date: 2003-01 Impact factor: 10.864

3. Randomised clinical trial: the clinical effects of a novel neurokinin receptor antagonist, DNK333, in women with diarrhoea-predominant irritable bowel syndrome.

Authors: S Zakko; G Barton; E Weber; C Dunger-Baldauf; A Rühl
Journal: Aliment Pharmacol Ther Date: 2011-04-20 Impact factor: 8.171

4. Gastrointestinal transit abnormalities are frequently detected in patients with unexplained GI symptoms at a tertiary centre.

Authors: R Sadik; P-O Stotzer; M Simrén; H Abrahamsson
Journal: Neurogastroenterol Motil Date: 2007-11-05 Impact factor: 3.598

5. Effects of pregabalin on visceral pain responses and colonic compliance in rats.

Authors: A Ravnefjord; M Brusberg; H Larsson; E Lindström; V Martínez
Journal: Br J Pharmacol Date: 2008-06-23 Impact factor: 8.739

6. Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome.

Authors: Viola Andresen; Michael Camilleri; Irene A Busciglio; April Grudell; Duane Burton; Sanna McKinzie; Amy Foxx-Orenstein; Caroline B Kurtz; Vineeta Sharma; Jeffrey M Johnston; Mark G Currie; Alan R Zinsmeister
Journal: Gastroenterology Date: 2007-07-03 Impact factor: 22.682

7. Post-infectious functional gastrointestinal disorders in children.

Authors: Miguel Saps; Licia Pensabene; Lucio Di Martino; Annamaria Staiano; Joshua Wechsler; Xiaotian Zheng; Carlo Di Lorenzo
Journal: J Pediatr Date: 2008-02-14 Impact factor: 4.406

8. SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents.

Authors: John Cuppoletti; Danuta H Malinowska; Kirti P Tewari; Qiu-Ju Li; Ann M Sherry; Myra L Patchen; Ryuji Ueno
Journal: Am J Physiol Cell Physiol Date: 2004-06-22 Impact factor: 4.249

Review 9. Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis.

Authors: A C Ford; N J Talley; P S Schoenfeld; E M M Quigley; P Moayyedi
Journal: Gut Date: 2008-11-10 Impact factor: 23.059

Brain-gut axis: from basic understanding to treatment of IBS and related disorders.

Review 1. Chronic constipation.

Review 2. A systematic review of neuroimaging data during visceral stimulation.

3. Randomised clinical trial: the clinical effects of a novel neurokinin receptor antagonist, DNK333, in women with diarrhoea-predominant irritable bowel syndrome.

4. Gastrointestinal transit abnormalities are frequently detected in patients with unexplained GI symptoms at a tertiary centre.

5. Effects of pregabalin on visceral pain responses and colonic compliance in rats.

6. Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome.

7. Post-infectious functional gastrointestinal disorders in children.

8. SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents.

Review 9. Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis.

10. Placebos without deception: a randomized controlled trial in irritable bowel syndrome.

Review 1. Hirschsprung disease - integrating basic science and clinical medicine to improve outcomes.

Review 2. Impact of psychological stress on irritable bowel syndrome.

Review 3. The role of AST-120 and protein-bound uremic toxins in irritable bowel syndrome: a therapeutic perspective.

Review 4. Aspects of the non-pharmacological treatment of irritable bowel syndrome.

Review 5. Irritable bowel syndrome: the evolution of multi-dimensional looking and multidisciplinary treatments.

Review 6. Brain-Gut Axis: Clinical Implications.

Review 7. Extra-intestinal and long term consequences of Giardia duodenalis infections.

Review 8. It's a gut feeling: how the gut microbiota affects the state of mind.

9. Linaclotide.

10. Irritable bowel syndrome and migraine: bystanders or partners?