Literature DB >> 2202751

The effects of amiodarone on thyroid hormone function: a review of the physiology and clinical manifestations.

H L Figge1, J Figge.   

Abstract

Amiodarone, an iodinated benzofuran derivative, is used for treatment of refractory cardiac arrhythmias. Certain features of the drug's structure resemble those of the biologically active thyroid hormone, triiodothyronine (T3). In addition, the drug has a variety of complex effects on thyroid hormone physiology, including a number of possible antagonistic effects on thyroid hormone function at the cellular level. The drug occasionally causes clinically overt hyperthyroidism and hypothyroidism. We review these effects and discuss their clinical implications.

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Year:  1990        PMID： 2202751     DOI： 10.1002/j.1552-4604.1990.tb01861.x

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN： 0091-2700            Impact factor:   3.126


  9 in total

Review 1.  Amiodarone-induced thyroid disorders: a clinical review.

Authors:  K C Loh
Journal:  Postgrad Med J       Date:  2000-03       Impact factor: 2.401

2.  High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment.

Authors:  S Mariotti; A Loviselli; S Murenu; F Sau; L Valentino; A Mandas; S Vacquer; E Martino; A Balestrieri; M E Lai
Journal:  J Endocrinol Invest       Date:  1999-01       Impact factor: 4.256

3.  Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment.

Authors:  Anne R Cappola; Akshay S Desai; Marco Medici; Lawton S Cooper; Debra Egan; George Sopko; Glenn I Fishman; Steven Goldman; David S Cooper; Samia Mora; Peter J Kudenchuk; Anthony N Hollenberg; Cheryl L McDonald; Paul W Ladenson
Journal:  Thyroid       Date:  2019-05-13       Impact factor: 6.568

4.  Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment.

Authors:  Anne R Cappola; Akshay S Desai; Marco Medici; Lawton S Cooper; Debra Egan; George Sopko; Glenn I Fishman; Steven Goldman; David S Cooper; Samia Mora; Peter J Kudenchuk; Anthony N Hollenberg; Cheryl L McDonald; Paul W Ladenson
Journal:  Circulation       Date:  2019-05-13       Impact factor: 29.690

5.  Use of plasma iodine assay for diagnosing thyroid disorders.

Authors:  P Allain; S Berre; N Krari; P Lainé-Cessac; A Le Bouil; N Barbot; V Rohmer; J C Bigorgne
Journal:  J Clin Pathol       Date:  1993-05       Impact factor: 3.411

Review 6.  Clinical use of sensitive assays for thyroid-stimulating hormone.

Authors:  P A Masters; R J Simons
Journal:  J Gen Intern Med       Date:  1996-02       Impact factor: 5.128

Review 7.  Amiodarone. An overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias.

Authors:  J Gill; R C Heel; A Fitton
Journal:  Drugs       Date:  1992-01       Impact factor: 9.546

Review 8.  A Review of the Pharmacokinetics of Levothyroxine for the Treatment of Hypothyroidism.

Authors:  Philippe Colucci; Corinne Seng Yue; Murray Ducharme; Salvatore Benvenga
Journal:  Eur Endocrinol       Date:  2013-03-15

9.  Incidence and pattern of thyroid dysfunction in patients on chronic amiodarone therapy: experience at a tertiary care centre in oman.

Authors:  H Farhan; A Albulushi; A Taqi; A Al-Hashim; K Al-Saidi; K Al-Rasadi; A Al-Mazroui; I Al-Zakwani
Journal:  Open Cardiovasc Med J       Date:  2013-11-29
  9 in total

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