Literature DB >> 22025539

Depression, anxiety, and COPD: the unexamined role of nicotine dependence.

Renee D Goodwin1, Kim L Lavoie, Adina R Lemeshow, Elizabeth Jenkins, E Sherwood Brown, David A Fedoronko.   

Abstract

INTRODUCTION: Previous studies have shown links between anxiety and depression and chronic obstructive pulmonary disease (COPD), but little is known about possible mechanisms of this association. The current study examined whether the observed relationship between anxiety and depression and COPD is explained by confounding due to cigarette smoking and lifetime nicotine dependence.
METHODS: Data were drawn from the National Comorbidity Survey Replication, a community-based representative sample of adults in the United States.
RESULTS: Analyses suggest that the association between anxiety disorders and COPD appears to be largely explained by confounding by former cigarette smoking and lifetime nicotine dependence. The association between mood disorders and COPD appears to be largely explained by confounding by lifetime nicotine dependence.
CONCLUSIONS: These findings provide initial evidence suggesting that the association between anxiety, depression, and COPD may be at least partly attributable to confounding by cigarette smoking and nicotine dependence. Efforts toward prevention of chronic lung disease may be more effective if treatment and prevention efforts aimed at smoking cessation address mental health problems.

Entities:  

Mesh:

Year:  2011        PMID: 22025539      PMCID: PMC3265744          DOI: 10.1093/ntr/ntr165

Source DB:  PubMed          Journal:  Nicotine Tob Res        ISSN: 1462-2203            Impact factor:   4.244


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Review 6.  The development of dependence on smoking in children.

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Review 2.  Pharmacological treatment of depression in older patients with chronic obstructive pulmonary disease: impact on the course of the disease and health outcomes.

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5.  Nicotine Dependence in Adolescence and Physical Health Symptoms in Early Adulthood.

Authors:  Pamela C Griesler; Mei-Chen Hu; Denise B Kandel
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Review 6.  Depression and anxiety in patients with COPD.

Authors:  Abebaw M Yohannes; George S Alexopoulos
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7.  Effects of 6-Week Use of Reduced-Nicotine Content Cigarettes in Smokers With and Without Elevated Depressive Symptoms.

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