Literature DB >> 22025387

Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases.

Rajesh Gumpena1, Chandan Kishor, Roopa Jones Ganji, Anthony Addlagatta.   

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Year:  2011        PMID： 22025387     DOI： 10.1002/cmdc.201100298

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  5 in total

1.  A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases.

Authors:  Ewelina Węglarz-Tomczak; Łukasz Berlicki; Małgorzata Pawełczak; Bogusław Nocek; Andrzej Joachimiak; Artur Mucha
Journal:  Eur J Med Chem       Date:  2016-04-09       Impact factor: 6.514

2.  Localization and enzyme kinetics of aminopeptidase N3 from Toxoplasma gondii.

Authors:  Wenhua Lu; Cheng Lu; Qian Zhang; Shinuo Cao; Zhaoxia Zhang; Honglin Jia; Jun Zheng
Journal:  Parasitol Res       Date:  2019-12-13       Impact factor: 2.289

3.  An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling.

Authors:  Ewelina Węglarz-Tomczak; Marcin Poręba; Anna Byzia; Łukasz Berlicki; Bogusław Nocek; Rory Mulligan; Andrzej Joachimiak; Marcin Drąg; Artur Mucha
Journal:  Biochimie       Date:  2012-11-03       Impact factor: 4.079

4.  Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases.

Authors:  Emmanuel Salomon; Marjorie Schmitt; Anil Kumar Marapaka; Athanasios Stamogiannos; Germain Revelant; Céline Schmitt; Sarah Alavi; Isabelle Florent; Anthony Addlagatta; Efstratios Stratikos; Céline Tarnus; Sébastien Albrecht
Journal:  Molecules       Date:  2018-10-11       Impact factor: 4.411

5.  Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.

Authors:  Stamatia Vassiliou; Ewelina Węglarz-Tomczak; Łukasz Berlicki; Małgorzata Pawełczak; Bogusław Nocek; Rory Mulligan; Andrzej Joachimiak; Artur Mucha
Journal:  J Med Chem       Date:  2014-09-22       Impact factor: 7.446
  5 in total

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