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Literature DB >> 22025056

Studying the mononuclear phagocyte system in the molecular age.

Andrew Chow¹, Brian D Brown, Miriam Merad.

Abstract

The mononuclear phagocyte system (MPS) comprises monocytes, macrophages and dendritic cells. Tissue phagocytes share several cell surface markers, phagocytic capability and myeloid classification; however, the factors that regulate the differentiation, homeostasis and function of macrophages and dendritic cells remain largely unknown. The purpose of this manuscript is to review the tools that are currently available and those that are under development to study the origin and function of mononuclear phagocytes.

Entities: Disease

Mesh：

Year: 2011 PMID： 22025056 DOI： 10.1038/nri3087

Source DB: PubMed Journal: Nat Rev Immunol ISSN： 1474-1733 Impact factor: 53.106

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