| Literature DB >> 22024947 |
Jean-Yves Petit1, Umberto Veronesi, Visnu Lohsiriwat, PierCarlo Rey, Giuseppe Curigliano, Stefano Martella, Cristina Garusi, Francesca De Lorenzi, Andrea Manconi, Edoardo Botteri, Florence Didier, Roberto Orecchia, Mario Rietjens.
Abstract
Nipple-sparing mastectomy (NSM) is a surgical protocol designed to reduce the disabling psychological effects of radical or skin-sparing mastectomy. The preservation of the nipple-areola complex produces a more-natural result of the breast reconstruction, but this preservation is suspected of increasing tumor local recurrence. To reduce this risk, different approaches have been proposed: restrict the inclusion criteria and/or add localized radiation therapy. The local recurrence rate in recent series of patients receiving NSM is comparable with the local recurrence rate in modified radical or skin-sparing mastectomies. Today, the quality of the subcutaneous mastectomy technique allows for a more radical glandular removal, especially in the retroareolar area; therefore, local recurrence is observed in 3-6% of patients at 5 years, consistent with traditional mastectomy.Entities:
Mesh:
Year: 2011 PMID: 22024947 DOI: 10.1038/nrclinonc.2011.159
Source DB: PubMed Journal: Nat Rev Clin Oncol ISSN: 1759-4774 Impact factor: 66.675