Literature DB >> 22024087

Effect of pyloric dilatation on gastric emptying after pylorus-preserving pancreaticoduodenectomy.

Miljenko Uravić1, Marko Zelić, Nenad Petrošić, Vlatka Sotošek Tokmadžić, Davor Stimac, Alan Sustić.   

Abstract

BACKGROUND/AIMS: Pylorus-preserving pancreaticoduodenectomy (PPPD) is the standard treatment for periampullary and pancreatic head tumors. Delayed gastric emptying (DGE) is the most common (ranging from 15-45%) but not life threatening complication and impairs patient recovery and prolongs the hospital stay after PPPD. The precise pathomechanism of DGE is still unclear. The aim of this study was to evaluate whether the method of pyloric dilatation performed at the time of PPPD could improve gastric emptying.
METHODOLOGY: Forty patients underwent PPPD for pancreatic or periampullary lesions from January 1999 to July 2004 were included in this study. In twenty patients mechanical dilatation of the pylorus after duodenal transaction was performed (PPPD+PD group) while in other twenty PPPD was not followed with pyloric dilatation (PPPD group). The incidence of DGE as well as other complications was analyzed. Delayed gastric emptying was defined as gastric stasis requiring nasogastric intubation for more than 4 postoperative days (POD), or the inability to tolerate a regular diet on the 8th POD.
RESULTS: Delayed gastric emptying occurred in seven (35%) out of the 20 patients in the PPPD group, while none of the 20 patients in the PPPD+PD group developed DGE.
CONCLUSIONS: Pyloric dilatation reduces DGE after PPPD enabling patients to return sooner to a normal diet.

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Year:  2011        PMID: 22024087     DOI: 10.5754/hge11163

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  1 in total

1.  Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity.

Authors:  Stefan Harmuth; Marlene Wewalka; Jens Juul Holst; Romina Nemecek; Sabine Thalhammer; Rainer Schmid; Klaus Sahora; Michael Gnant; Johannes Miholić
Journal:  J Gastrointest Surg       Date:  2013-09-04       Impact factor: 3.452

  1 in total

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