Wang Jian1, Liu Heng, Qi Qing Hui. 1. Department of General Surgery, The General Hospital of Tianjin Medical University, Tianjin, China. simpbart@yahoo.cn
Abstract
BACKGROUND/AIMS: The aim of this study was to investigate the effect of Da-Cheng-Qi-Tang (DCQT) on the gastrointestinal motilityafter abdominal surgery in humans. METHODOLOGY:Thirty-three patients with abdominal surgery and 36 patients with cholecystectomy were divided into DCQT and control groups at random. Electrogastrography (EGG) and antroduodenojejunal manometry were performed and the level of plasma ghrelin were measured by ELISA. RESULTS: On the operative day, the ratio of EGG normal slow waves in DCQT group was higher than in control group (p<0.05). The power of EGG in DCQT group was higher than in control group on the 2nd and 3rd postoperative day (p<0.05). The percentage of normal bowel peristalsis was significantly higher in the DCQT group than in control group (p<0.01). On the 1st and 2nd postoperative day, the power of Phase III of migrating motor complex (MMC) in the proximal jejunum in DCQT group was significantly higher than in control group (p<0.05). On the 3rd and 5th postoperative day, the plasma ghrelin level in the DCQT group was significantly higher than in the control group (p<0.05). CONCLUSIONS:DCQT could improve gastric dysrythmia, enhance gastrointestinal motility and adjust the synchronized recovery of the alimentary tract and increase plasma ghrelin after abdominal surgery.
RCT Entities:
BACKGROUND/AIMS: The aim of this study was to investigate the effect of Da-Cheng-Qi-Tang (DCQT) on the gastrointestinal motility after abdominal surgery in humans. METHODOLOGY: Thirty-three patients with abdominal surgery and 36 patients with cholecystectomy were divided into DCQT and control groups at random. Electrogastrography (EGG) and antroduodenojejunal manometry were performed and the level of plasma ghrelin were measured by ELISA. RESULTS: On the operative day, the ratio of EGG normal slow waves in DCQT group was higher than in control group (p<0.05). The power of EGG in DCQT group was higher than in control group on the 2nd and 3rd postoperative day (p<0.05). The percentage of normal bowel peristalsis was significantly higher in the DCQT group than in control group (p<0.01). On the 1st and 2nd postoperative day, the power of Phase III of migrating motor complex (MMC) in the proximal jejunum in DCQT group was significantly higher than in control group (p<0.05). On the 3rd and 5th postoperative day, the plasma ghrelin level in the DCQT group was significantly higher than in the control group (p<0.05). CONCLUSIONS: DCQT could improve gastric dysrythmia, enhance gastrointestinal motility and adjust the synchronized recovery of the alimentary tract and increase plasma ghrelin after abdominal surgery.