| Literature DB >> 22022991 |
Sang Hwi Lee1, In Su Kim, Qing Ri Li, Guang Ri Dong, Lak Shin Jeong, Young Hoon Jung.
Abstract
The stereoselective amination of various chiral benzylic ethers using chlorosulfonyl isocyanate is developed, and the application of this method to the total synthesis of a potent antidepressant, (+)-sertraline, from readily available 1-naphthol is also described.Entities:
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Year: 2011 PMID： 22022991 DOI： 10.1021/jo201794k
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354