Literature DB >> 22022955

Electroreductive intramolecular coupling of phthalimides with aromatic aldehydes: application to the synthesis of lennoxamine.

Naoki Kise1, Shinsaku Isemoto, Toshihiko Sakurai.   

Abstract

The electroreductive intramolecular coupling of phthalimides with aromatic aldehydes in the presence of chlorotrimethylsilane and triethylamine led to five-, six-, and seven-membered cyclized products (58-84%). The electroreductive cyclization was applied to the total synthesis of lennoxamine.
© 2011 American Chemical Society

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Year:  2011        PMID： 22022955     DOI： 10.1021/jo2018735

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance.

Authors:  Ming Yan; Yu Kawamata; Phil S Baran
Journal:  Chem Rev       Date:  2017-10-09       Impact factor: 60.622

2.  Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives.

Authors:  Muhammad Idham Darussalam Mardjan; Muhamad Fadhly Hariadi; Indah Mutiara Putri; Nilna Amalia Musyarrofah; Muflihah Salimah; Bambang Purwono; Laurent Commeiras
Journal:  RSC Adv       Date:  2022-06-29       Impact factor: 4.036

3.  Electroreductive Intermolecular Coupling of 4-Quinolones with Benzophenones: Synthesis of 2-Substituted 4-Quinolones.

Authors:  Naoki Kise; Yoshie Yoshimura; Tatsuhiro Manto; Toshihiko Sakurai
Journal:  ACS Omega       Date:  2019-11-15
  3 in total

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