Literature DB >> 22021933

Polypeptide grafted hyaluronan: A self-assembling comb-branched polymer constructed from biological components.

Madhuvanthi A Kandadai1, Rajasekhar Anumolu, Xiaojun Wang, Durairaj Baskaran, Leonard F Pease, Dmitry Bedrov, Grant D Smith, Jimmy W Mays, Jules J Magda.   

Abstract

Rheological evidence is provided demonstrating that covalent grafting of monodisperse isotactic poly(L-leucine) branches onto linear hyaluronan (HA) polysaccharide chains yields comb-branched HA chains that self-assemble into long-lived physical networks in aqueous solutions driven by hydrophobic interactions between poly(L-leucine) chains. This is in stark contrast to native (unmodified) HA solutions which exhibit no tendency to form long-lived physical networks.

Entities:  

Year:  2011        PMID: 22021933      PMCID: PMC3196612          DOI: 10.1016/j.eurpolymj.2011.07.017

Source DB:  PubMed          Journal:  Eur Polym J        ISSN: 0014-3057            Impact factor:   4.598


  14 in total

1.  Hyaluronan: Preparation, Structure, Properties, and Applications.

Authors:  Lubomír Lapcík; Stefaan De Smedt; Joseph Demeester; Peter Chabrecek
Journal:  Chem Rev       Date:  1998-12-17       Impact factor: 60.622

2.  Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles.

Authors:  Andrew P Nowak; Victor Breedveld; Lisa Pakstis; Bulent Ozbas; David J Pine; Darrin Pochan; Timothy J Deming
Journal:  Nature       Date:  2002-05-23       Impact factor: 49.962

Review 3.  Experimental approaches to hyaluronan structure.

Authors:  Mary K Cowman; Shiro Matsuoka
Journal:  Carbohydr Res       Date:  2005-04-11       Impact factor: 2.104

4.  Microrheological detection of protein unfolding.

Authors:  Raymond S Tu; Victor Breedveld
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2005-10-13

5.  Amphoteric hyaluronic acid derivative for targeting gene delivery.

Authors:  Jing Yao; Ying Fan; Ronghui Du; Jianping Zhou; Yun Lu; Wei Wang; Jin Ren; Xiaojing Sun
Journal:  Biomaterials       Date:  2010-09-22       Impact factor: 12.479

6.  The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels.

Authors:  Yuguo Lei; Shiva Gojgini; Jonathan Lam; Tatiana Segura
Journal:  Biomaterials       Date:  2010-10-12       Impact factor: 12.479

7.  Polypeptide grafted hyaluronan: synthesis and characterization.

Authors:  Xiaojun Wang; Jamie Messman; Jimmy W Mays; Durairaj Baskaran
Journal:  Biomacromolecules       Date:  2010-09-13       Impact factor: 6.988

8.  Self-assembled hyaluronic acid nanoparticles for active tumor targeting.

Authors:  Ki Young Choi; Hyunjin Chung; Kyung Hyun Min; Hong Yeol Yoon; Kwangmeyung Kim; Jae Hyung Park; Ick Chan Kwon; Seo Young Jeong
Journal:  Biomaterials       Date:  2009-09-26       Impact factor: 12.479

9.  Nanoscale double emulsions stabilized by single-component block copolypeptides.

Authors:  Jarrod A Hanson; Connie B Chang; Sara M Graves; Zhibo Li; Thomas G Mason; Timothy J Deming
Journal:  Nature       Date:  2008-09-04       Impact factor: 49.962

10.  Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel.

Authors:  Xiao Zheng Shu; Kaustabh Ghosh; Yanchun Liu; Fabio S Palumbo; Yi Luo; Richard A Clark; Glenn D Prestwich
Journal:  J Biomed Mater Res A       Date:  2004-02-01       Impact factor: 4.396

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