Literature DB >> 220184

Lymphocyte surface modulation and glycosphingolipids.

C C Curtain.   

Abstract

Using the fluorescent antibody method, identical localization of ligand and glycosphingolipids was found in human peripheral blood B lymphocytes patched and capped with polyvalent anti-immunoglobulin. cAMP also showed the same pattern of localization. It is suggested that glycosphingolipids are hydrogen bonded to receptor-bearing membrane macromolecules and are borne with them into the ligand-induced patches and caps. Here the asymmetric carbon chains of the glycosphingolipids modify the local lipid environment, leading to activation of the adenyl cyclase in the membrane which produces the cAMP.

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Year:  1979        PMID: 220184      PMCID: PMC1457657     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  20 in total

1.  The chromatographic purification of fluorescein-antibody.

Authors:  C C CURTAIN
Journal:  J Histochem Cytochem       Date:  1961-09       Impact factor: 2.479

2.  A simple chromatographic method for preparation of gamma globulin.

Authors:  H B LEVY; H A SOBER
Journal:  Proc Soc Exp Biol Med       Date:  1960-01

Review 3.  Cyclic nucleotide immunocytochemistry.

Authors:  A L Steiner; S H Ong; H J Wedner
Journal:  Adv Cyclic Nucleotide Res       Date:  1976

4.  Transmembrane interactions and the mechanism of capping of surface receptors by their specific ligands.

Authors:  L Y Bourguignon; S J Singer
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

5.  Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes.

Authors:  G Gabbiani; C Chaponnier; A Zumbe; P Vassalli
Journal:  Nature       Date:  1977-10-20       Impact factor: 49.962

6.  Identification of resting human T and B lymphocytes by acid alpha-naphthyl acetate esterase staining combined with rosette formation with Staphylococcus aureus strain Cowan 1.

Authors:  A Ranki; T H Tötterman; P Häyry
Journal:  Scand J Immunol       Date:  1976       Impact factor: 3.487

7.  Immune reactivities of antibodies against glycolipids--I. Properties of anti-galactocerebroside antibodies purified by a novel technique of affinity binding to liposomes.

Authors:  C R Alving; R L Richards
Journal:  Immunochemistry       Date:  1977-05

8.  Glycolipids in model membranes. Spin label and freeze-etch studies.

Authors:  F J Sharom; D G Barratt; A E Thede; C W Grant
Journal:  Biochim Biophys Acta       Date:  1976-12-02

Review 9.  Biosynthesis and function of gangliosides.

Authors:  P H Fishman; R O Brady
Journal:  Science       Date:  1976-11-26       Impact factor: 47.728

10.  Lymphocyte surface modulation and cyclic nucleotides I. Topographic correlation of cyclic adenosine 3':5'-monophosphate and immunoglobulin immunofluorescence during lymphocyte capping.

Authors:  H S Earp; P D Utsinger; W J Yount; M Logue; A L Steiner
Journal:  J Exp Med       Date:  1977-04-01       Impact factor: 14.307

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  2 in total

1.  Mobility of the human T lymphocyte surface molecules CD3, CD4, and CD8: regulation by a cAMP-dependent pathway.

Authors:  G M Kammer; C A Boehm; S A Rudolph; L A Schultz
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

Review 2.  Brain and thymus gangliosides: their molecular diversity and its biological implications and a dynamic annular model for their function in cell surface membranes.

Authors:  Y Nagai; M Iwamori
Journal:  Mol Cell Biochem       Date:  1980-02-08       Impact factor: 3.396

  2 in total

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