Literature DB >> 22017591

Differentiation pathways in carcinogenesis and in chemo- and radioresistance.

M Janikova1, J Skarda.   

Abstract

Cancer stem cells (CSCs) share many features with embryonic stem cells (ESCs) such as the ability for self-renewal and differentiation. Signaling pathways that are involved in these processes are also involved in chemo- and radioresistance (e.g. Wnt, Notch and Hedgehog pathways). This review is focused on the influence of three important differentiation pathways on carcinogenesis and on chemo- and radioresistance in ESCs and CSCs.

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Year:  2012        PMID： 22017591     DOI： 10.4149/neo_2012_002

Source DB:  PubMed          Journal:  Neoplasma        ISSN： 0028-2685            Impact factor:   2.575


  18 in total

1.  Nuclear localizaiton of β-catenin is associated with poor survival and chemo-/radioresistance in human cervical squamous cell cancer.

Authors:  Yanna Zhang; Bangzhong Liu; Qingyu Zhao; Teng Hou; Xin Huang
Journal:  Int J Clin Exp Pathol       Date:  2014-06-15

2.  Inhibition of transient receptor potential channel 5 reverses 5-Fluorouracil resistance in human colorectal cancer cells.

Authors:  Teng Wang; Zhen Chen; Yifei Zhu; Qiongxi Pan; Yanjun Liu; Xiaowei Qi; Linfang Jin; Jian Jin; Xin Ma; Dong Hua
Journal:  J Biol Chem       Date:  2014-11-17       Impact factor: 5.157

Review 3.  Clinically relevant radioresistant cell line: a simple model to understand cancer radioresistance.

Authors:  Yoshikazu Kuwahara; Mehryar Habibi Roudkenar; Yusuke Urushihara; Yohei Saito; Kazuo Tomita; Amaneh Mohammadi Roushandeh; Tomoaki Sato; Akihiro Kurimasa; Manabu Fukumoto
Journal:  Med Mol Morphol       Date:  2017-10-24       Impact factor: 2.309

4.  Honokiol as a Radiosensitizing Agent for Colorectal cancers.

Authors:  Zhiyun He; Dharmalingam Subramaniam; Zhongtao Zhang; Youcheng Zhang; Shrikant Anant
Journal:  Curr Colorectal Cancer Rep       Date:  2013-12

5.  UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest-Like Cells via Suppression of Notch.

Authors:  Mizuho Fukunaga-Kalabis; Denitsa M Hristova; Joshua X Wang; Ling Li; Markus V Heppt; Zhi Wei; Alexandra Gyurdieva; Marie R Webster; Masahiro Oka; Ashani T Weeraratna; Meenhard Herlyn
Journal:  J Invest Dermatol       Date:  2015-02-23       Impact factor: 8.551

Review 6.  Hedgehog signaling in prostate cancer and its therapeutic implication.

Authors:  Annelies Gonnissen; Sofie Isebaert; Karin Haustermans
Journal:  Int J Mol Sci       Date:  2013-07-04       Impact factor: 5.923

Review 7.  Salinomycin as a drug for targeting human cancer stem cells.

Authors:  Cord Naujokat; Roman Steinhart
Journal:  J Biomed Biotechnol       Date:  2012-11-21

Review 8.  Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened.

Authors:  Annelies Gonnissen; Sofie Isebaert; Karin Haustermans
Journal:  Oncotarget       Date:  2015-06-10

9.  Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance.

Authors:  Chang-Nim Im; Byeong Mo Kim; Eun-Yi Moon; Da-Won Hong; Joung Whan Park; Sung Hee Hong
Journal:  Genomics Inform       Date:  2013-12-31

Review 10.  ABC transporters in CSCs membranes as a novel target for treating tumor relapse.

Authors:  Laura Zinzi; Marialessandra Contino; Mariangela Cantore; Elena Capparelli; Marcello Leopoldo; Nicola A Colabufo
Journal:  Front Pharmacol       Date:  2014-07-10       Impact factor: 5.810
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